ArticleJournal of cardiothoracic surgery2021
Hepatic dysfunction in patients who received acute DeBakey type I aortic dissection repair surgery: incidence, risk factors, and long-term outcomes.
Article in Journal of cardiothoracic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Risk factors and prognosis of postoperative hepatic dysfunction after Stanford type A aortic dissection repair: a systematic review and meta-analysis.Journal of cardiothoracic surgery · 2026Pooled it
- Effect of preoperative model for end-stage liver disease score in cardiac valve surgery.General thoracic and cardiovascular surgery · 2026Article
- Nomogram prediction of acute kidney injury following modified Morrow myectomy in hypertrophic obstructive cardiomyopathy: insights from 12 years of outcomes.BMC cardiovascular disorders · 2026Article
- Reduction of maximal false lumen area ratio by interactive cannulation perfusion in DeBakey type I acute aortic dissection repair.Journal of cardiovascular and thoracic research · 2025Article
- Application of model for end-stage liver disease as disease classification in cardiac valve surgery: a retrospective study based on the INSPIRE database.Journal of thoracic disease · 2024Article
- Hepatic dysfunction and adverse outcomes after total arch repair of acute type a aortic dissection: application of the MELD-XI score.BMC cardiovascular disorders · 2022Article
- Hyperbilirubinemia after surgical repair for acute type a aortic dissection: A propensity score-matched analysis.Frontiers in physiology · 2022Article
- Persistent Liver Dysfunction in Pediatric Patients After Total Cavopulmonary Connection Surgery.Frontiers in cardiovascular medicine · 2022Article
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6 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundHepatic dysfunction (HD) increases the morbidity and mortality rates after cardiac surgery. However, few studies have investigated the association between HD and acute DeBakey type I aortic dissection (ADIAD) surgery. This retrospective study aimed to identify risk factors for developing HD in patients who received acute type I aortic dissection repair and its consequences.
methodsA total of 830 consecutive patients who received ADIAD surgery from January 2014 to December 2019 at our center were screened for this study. The End-Stage Liver Disease (MELD) score more than 14 was applied to identify postoperative HD. Logistic regression model was applied to identify risk factors for postoperative HD, Kaplan-Meier survival analysis and Cox proportional hazards regression assay were conducted to analyze the association between HD and postoperative long-term survival.
resultsAmong 634 patients who eventually enrolled in this study, 401 (63.2%) experienced postoperative HD with a 30-Day mortality of 15.5%. Preoperative plasma fibrinogen level (PFL) [odds ratio (OR): 0.581, 95% confidence interval (CI): 0.362-0.933, P = 0.025], serum creatinine (sCr) on admission (OR: 1.050, 95% CI 1.022-1.079, P < 0.001), cardiopulmonary bypass (CPB) time (OR: 1.017, 95% CI 1.010-1.033, P = 0.039), and postoperative mechanical ventilation (MV) duration (OR: 1.019, 95% CI 1.003-1.035, P = 0.020) were identified as independent risk factors for developing postoperative HD by multivariate analyses. In addition, the Kaplan-Meier analysis indicated that the long-term survival rate was significantly different between patients with or without postoperative HD. However, the hazard ratios of long-term survival for these two groups were not significantly different.
conclusionsHD was a common complication after ADIAD surgery and associated with an increasing 30-Day mortality rate. Decreased PFL, elevated sCr, prolonged CPB duration, and longer postoperative MV time were independent risk factors for postoperative HD.
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