Evidence map›Paper›PMID 34628863›Full record

ArticleJournal of natural products2021

Rufomycins or Ilamycins: Naming Clarifications and Definitive Structural Assignments.

Bin Zhou, Prabhakar S Achanta, Gauri Shetye, Shao-Nong Chen, Hyun Lee, Ying-Yu Jin, Jinhua Cheng, Mi-Jin Lee, Joo-Won Suh, Sanghyun Cho and 3 more

Abstract read
In one paragraph

Article in Journal of natural products, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Fighting Antimicrobial Resistance: Innovative Drugs in Antibacterial Research.Angewandte Chemie (International ed. in English) · 2025
    Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. New Rufomycins fromOrganic letters · 2022
    Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Bin ZhouInstitute for Tuberculosis Research, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Prabhakar S AchantaDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Gauri ShetyeInstitute for Tuberculosis Research, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Shao-Nong ChenInstitute for Tuberculosis Research, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0003-0748-0863
Hyun LeeInstitute for Tuberculosis Research, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0003-2570-8120
Ying-Yu JinMan Bang Bio Co., Ltd., Subsidiary of Myongji University Technology Holdings Ltd., Cheoin-gu, Yongin-si, Gyeonggi-do 17058, Republic of Korea.
Jinhua ChengMyongji Bioefficacy Research Center, Myongji University, Cheoin-gu, Yongin-si, Gyeonggi-do 17058, Republic of Korea.
Mi-Jin LeeMyongji Bioefficacy Research Center, Myongji University, Cheoin-gu, Yongin-si, Gyeonggi-do 17058, Republic of Korea.
Joo-Won SuhMyongji Bioefficacy Research Center, Myongji University, Cheoin-gu, Yongin-si, Gyeonggi-do 17058, Republic of Korea.
Sanghyun ChoInstitute for Tuberculosis Research, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0003-0926-6246
Scott G FranzblauInstitute for Tuberculosis Research, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0002-8698-0243
Guido F PauliInstitute for Tuberculosis Research, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0003-1022-4326
James B McAlpineInstitute for Tuberculosis Research, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0003-1696-8828

Funding

UIC: In vitro In vivo Mtb PharmacologyU19AI142735 · NIAID · GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT · PI UPTON, ANNA · 2019 to 2023
$28.5M
NIAID NIH HHS U19 AI142735
6 · The paper itself

Abstract

Rufomycin and ilamycin are synonymous for the same class of cyclopeptides, currently encompassing 33 structurally characterized isolates and 9 semisynthetic derivatives. Elucidation of new structures prioritized the consolidation of the names and established the structures of four diastereoisomeric rufomycins with a 2-piperidinone, named rufomycins 4-7, including full

Indexed as

Antitubercular AgentsMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsMolecular StructureMycobacterium tuberculosisOligopeptidesPeptides, CyclicTerminology as TopicAntitubercular AgentsOligopeptidesPeptides, Cyclicrufomycin

Identifiers

PMID34628863
PMCPMC8865217

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.