Evidence map›Paper›PMID 34628556›Full record

ArticleEndocrine2022

Olfactory disfunction and diabetic complications in type 2 diabetic patients: a pilot study.

Francesco Mozzanica, Anna Ferrulli, Stela Vujosevic, Alessandro Montuori, Arianna Cardella, Andrea Preti, Federico Ambrogi, Antonio Schindler, Ileana Terruzzi, Francesco Ottaviani and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Endocrine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Olfactory function in diabetes mellitus.Journal of clinical & translational endocrinology · 2024
    Review
  5. Diabetes Mellitus, Kidney Disease, and Sense of Taste.Deutsches Arzteblatt international · 2023
    Article
  6. Article
  7. Application of Metabolomics in Various Types of Diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Francesco MozzanicaDepartment of Otorhinolaryngology, IRCCS Multimedica, Milan, Italy. francesco.mozzanica@gmail.com.ORCID http://orcid.org/0000-0003-2591-4063
Anna FerrulliDepartment of Endocrinology, Nutrition and Metabolic Diseases, IRCCS Multimedica, Milan, Italy.
Stela VujosevicDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Alessandro MontuoriDepartment of Otorhinolaryngology, IRCCS Multimedica, Milan, Italy.
Arianna CardellaDepartment of Otorhinolaryngology, IRCCS Multimedica, Milan, Italy.
Andrea PretiDepartment of Otorhinolaryngology, IRCCS Multimedica, Milan, Italy.
Federico AmbrogiDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Antonio SchindlerDepartment of Biomedical and Clinical sciences "L. Sacco", Luigi Sacco University Hospital, University of Milan, Milan, Italy.
Ileana TerruzziDepartment of Endocrinology, Nutrition and Metabolic Diseases, IRCCS Multimedica, Milan, Italy.
Francesco OttavianiDepartment of Otorhinolaryngology, IRCCS Multimedica, Milan, Italy.
Livio LuziDepartment of Endocrinology, Nutrition and Metabolic Diseases, IRCCS Multimedica, Milan, Italy.
University of Milan · ITMultiMedica · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeScarce information on the prevalence and characteristics of olfactory disfunction (OD) in type 2 diabetic (T2D) patients are available. The aims of this study were (1) to assess the olfactory function in T2D patients and to compare it with a control group of individuals without T2D, and (2) to evaluate the differences in OD within T2D patients according to the presence of diabetic complications.

methodsA group of 39 T2D patients and a control group of 39 healthy individuals were enrolled. Each subject underwent an evaluation of the olfactory performance using the Sniffing Olfactory Screening Test (SOST) and completed a questionnaire assessing the subjective perception of olfaction. According to the presence of diabetic complications, the group of T2D patients was divided into two subgroups. Non-parametric tests and regression analysis were used for statistical analysis.

resultsNo differences in the subjective perception of olfaction were demonstrated among T2D patients (with and without complications) and controls. A significant difference for the SOST score was demonstrated among the different groups. In particular, OD was more frequent in T2D patients than in controls. In addition, OD was far more frequent in T2D patients with complications. Regression analysis did not demonstrate any significant association between OD and clinical/demographic characteristics of T2D patients.

conclusionT2D patients were more frequently affected by OD. The subgroup analysis suggested a possible relationship between OD and diabetic complications since patients with T2D diabetic complications demonstrated lower olfactory abilities than controls subjects and T2D patients without diabetic complications.

Indexed as

Diabetes ComplicationsDiabetes Mellitus, Type 2Olfaction DisordersHumansPilot ProjectsSmellDiabetesDiabetic complicationOlfaction

Identifiers

PMID34628556
PMCPMC8501919
OpenAlexW3205019601

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.