Evidence map›Paper›PMID 34628551›Full record

ArticleCell and tissue banking2022

Lyophilized amniotic membrane graft for primary pterygium surgery: preliminary results.

Noelia Sabater-Cruz, Eva Martinez-Conesa, Anna Vilarrodona, Ricardo P Casaroli-Marano

Abstract read
PubMed Publisher
In one paragraph

Article in Cell and tissue banking, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Precut disc of lyophilized amniotic membrane for recurrent full thickness macular hole management.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  2. Article
  3. Review
  4. Review
  5. Solving STODS-Surgical Temporary Ocular Discomfort Syndrome.Diagnostics (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Noelia Sabater-CruzHospital Clinic de Barcelona, C/ Sabino de Arana S/N, 08028, Barcelona, Spain. noelia.sabater@gmail.com.ORCID http://orcid.org/0000-0003-3700-602X
Eva Martinez-ConesaBarcelona Tissue Bank (BST-BTB), Barcelona, Spain.
Anna VilarrodonaBarcelona Tissue Bank (BST-BTB), Barcelona, Spain.
Ricardo P Casaroli-MaranoHospital Clinic de Barcelona, C/ Sabino de Arana S/N, 08028, Barcelona, Spain.ORCID http://orcid.org/0000-0003-1812-9323
Hospital Clínic de Barcelona · ESInstitut d'Investigacions Biomèdiques de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the tolerability, safety and efficacy of new lyophilized amniotic membrane (LAM) presentation for ocular use. A prospective case-series cohort of four patients with primary nasal pterygium which undergone excision and LAM implantation was evaluated for complications and clinical outcomes. Surgical manipulation of LAM was also assessed. LAM was stiff and easy to manipulate as well as no tearing occurred during surgery or suturing. Ocular comfort was checked and similar among those patients with LAM glued or sutured. After 12 months, there were no issues about tolerability or adverse events. Lower cosmetic outcomes (recurrence) were stated in 3 patients. Our study showed that LAM could be an effective alternative to cryopreserved amniotic membrane for graft after pterygium excision surgery. Its main advantage, storage at room temperature, can make it of immediate availability. Further studies comparing clinical outcomes of pterygium surgery with cryopreserved amniotic membrane versus LAM would confirm the benefits of the last.

Indexed as

PterygiumAmnionConjunctivaFollow-Up StudiesHumansRecurrenceTransplantation, AutologousTreatment OutcomeCryopreserved amniotic membraneEye bankLyophilized amniotic membranePterygiumRecurrenceTissue bank

Identifiers

PMID34628551
OpenAlexW3207631057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.