ArticleInternational journal of medical informatics2021
Previewable Contract-Based On-Chain X-Ray Image Sharing Framework for Clinical Research.
Article in International journal of medical informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Distributed cross-learning for equitable federated models - privacy-preserving prediction on data from five California hospitals.Nature communications · 2025Article
- Distributed, immutable, and transparent biomedical limited data set request management on multi-capacity network.Journal of the American Medical Informatics Association : JAMIA · 2025Article
- Blockchain-enabled immutable, distributed, and highly available clinical research activity logging system for federated COVID-19 data analysis from multiple institutions.Journal of the American Medical Informatics Association : JAMIA · 2023Article
- Quorum-based model learning on a blockchain hierarchical clinical research network using smart contracts.International journal of medical informatics · 2023Article
- The evolving privacy and security concerns for genomic data analysis and sharing as observed from the iDASH competition.Journal of the American Medical Informatics Association : JAMIA · 2022Article
- Predicting COVID-19 county-level case number trend by combining demographic characteristics and social distancing policies.JAMIA open · 2022Article
- Detecting model misconducts in decentralized healthcare federated learning.International journal of medical informatics · 2022Article
- CertificateChain: decentralized healthcare training certificate management system using blockchain and smart contracts.JAMIA open · 2022Article
- Federated Learning in Glaucoma: A Comprehensive Review and Future Perspectives.Ophthalmology. GlaucomaReview
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
backgroundAn image sharing framework is important to support downstream data analysis especially for pandemics like Coronavirus Disease 2019 (COVID-19). Current centralized image sharing frameworks become dysfunctional if any part of the framework fails. Existing decentralized image sharing frameworks do not store the images on the blockchain, thus the data themselves are not highly available, immutable, and provable. Meanwhile, storing images on the blockchain provides availability/immutability/provenance to the images, yet produces challenges such as large-image handling, high viewing latency while viewing images, and software inconsistency while storing/loading images.
objectiveThis study aims to store chest x-ray images using a blockchain-based framework to handle large images, improve viewing latency, and enhance software consistency. BASIC PROCEDURES: We developed a splitting and merging function to handle large images, a feature that allows previewing an image earlier to improve viewing latency, and a smart contract to enhance software consistency. We used 920 publicly available images to evaluate the storing and loading methods through time measurements. MAIN
findingsThe blockchain network successfully shares large images up to 18 MB and supports smart contracts to provide code immutability, availability, and provenance. Applying the preview feature successfully shared images 93% faster than sharing images without the preview feature. PRINCIPAL
conclusionsThe findings of this study can guide future studies to generalize our framework to other forms of data to improve sharing and interoperability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.