Evidence map›Paper›PMID 34628152›Full record

Trial reportChild abuse & neglect2021

Mental health benefits of a 1-week intensive multimodal group program for adolescents with multiple adverse childhood experiences.

Susana Roque-Lopez, Elkin Llanez-Anaya, María Jesús Álvarez-López, Megan Everts, Daniel Fernández, Richard J Davidson, Perla Kaliman

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Child abuse & neglect, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07033520 (Effects of Online Mindfulness-Based Cognitive Therapy on Pain, Stress-Related Symptoms, and Functionality in Adults With Chronic Migraine and Adverse Childhood Experiences at the International Hospital of Colombia), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07033520 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Online Mindfulness-Based Cognitive Therapy on Pain, Stress-Related Symptoms, and Functionality in Adults With Chronic Migraine and Adverse Childhood Experiences at the International Hospital of Colombia

TypeinterventionalSponsorFundación Cardiovascular de ColombiaRan2025 to 2025Enrolled60ConditionsChronic Migraine, Adverse Childhood Experiences, Depression, AnxietyArmsOnline Mindfulness-Based Cognitive Therapy
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Susana Roque-LopezAssociation Innocence In Danger Colombia (IIDC), 33 Avenue Saint Charles, 34090 Montpellier, France.
Elkin Llanez-AnayaUniversidad de Santander, Facultad de Ciencias Médicas y Salud, Instituto de Investigación Masira, Bucaramanga, Colombia.
María Jesús Álvarez-LópezJacinto Benavente 3, 08100 Mollet del Valles, Spain.
Megan EvertsAssociation Innocence In Danger Colombia (IIDC), 33 Avenue Saint Charles, 34090 Montpellier, France.
Daniel FernándezSerra Húnter fellow. Department of Statistics and Operations Research & IMTech. Universitat Politècnica de Catalunya · BarcelonaTech (UPC). CIBERSAM. Spain.
Richard J DavidsonCenter for Healthy Minds, University of Wisconsin-Madison, 625 W. Washington Ave., Madison, WI 53703, United States of America.
Perla KalimanCenter for Healthy Minds, University of Wisconsin-Madison, 625 W. Washington Ave., Madison, WI 53703, United States of America; Universitat Oberta de Catalonia (UOC), Rambla del Poblenou, 156, 08018 Barcelona, Spain. Electronic address: pkaliman@uoc.edu.
University of Wisconsin–Madison · USCentro de Investigación Biomédica en Red de Salud Mental · ESInstitut de Seguretat Pública de Catalunya · ESUniversidad De Santander · CO

Funding

Neural Substrates of Affective Style and Emotion RegulationR01MH043454 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI DAVIDSON, RICHARD J, SCHAEFER, STACEY M · 1989 to 2022
$9.6M
NIMH NIH HHS R01 MH043454
6 · The paper itself

Abstract

backgroundAdverse childhood experiences (ACEs) are associated with a wide range of diseases, unsafe behavior and shorter life expectancy. However, there is scarce evidence on effective interventions for children or adolescents who report multiple ACEs, including abuse, neglect and household dysfunction.

objectiveThe aim of this study was to evaluate the mental health outcomes of a multimodal program designed for adolescents with multiple ACEs.

participantsForty-four girls (aged 13-16 years, mean ACE score > 5) were randomized to an intervention group or a care-as-usual control group.

methodsThe intervention included mindfulness-based practices, expressive arts and EMDR (Eye Movement Desensitization and Reprocessing Integrative) group treatment. We used questionnaires for adolescents to assess trauma (SPRINT, CPSS) and attention/awareness-related outcomes (MAAS-A) at baseline (T1), post-intervention (T2) and two-months post-discharge (T3).

resultsLinear mixed effects model analyses showed significant Group by Time interactions on all the scales (F = 11.0, p = 0.015; F = 12.5 p < 0.001; and F = 6.4, p = 0.001, for SPRINT, CPSS and MAAS-A, respectively). After completing the program, the intervention group showed significant reduction in trauma-related outcomes (SPRINT, Δ%

conclusionsResults presented here support this multimodal group intervention as a feasible and promising program for reducing the psychological burden in adolescents with a history of multiple ACEs.

Indexed as

Adverse Childhood ExperiencesEye Movement Desensitization ReprocessingAdolescentAftercareChildFemaleHumansMental HealthPatient DischargeAdolescenceAdverse childhood experienceEMDRIntegrativeMindfulnessPTSD

Identifiers

PMID34628152
PMCPMC8627589
OpenAlexW3202502617

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.