Evidence map›Paper›PMID 34628071›Full record

ArticlePhotodiagnosis and photodynamic therapy2021

Intranasal photobiomodulation therapy for COVID-19-related olfactory dysfunction: A Brazilian multicenter case series.

Luís Eduardo Silva Soares, Milena Miranda Goulart Guirado, Giuseppina Berlingieri, Marcia Christina Camargo Hernandes Ramires, Luciana Aparecida de Oliveira P Lyra, Inessa Solek Teixeira, Patrícia Costa Oliveira, Ricardo Yudi Tateno, Luiz Felipe Palma, Luana Campos

Abstract readMulticenter Study
In one paragraph

Article in Photodiagnosis and photodynamic therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luís Eduardo Silva SoaresGraduate Program in Biomedical Engineering, University of Vale do Paraíba (UNIVAP), Research and Development Institute (IP&D). São José dos Campos, SP, Brazil; Study Group of Laser and Health Institute, São Paulo, SP, Brazil.
Milena Miranda Goulart GuiradoStudy Group of Laser and Health Institute, São Paulo, SP, Brazil; Doutor José de Carvalho Florence Hospital, São José dos Campos, SP, Brazil.
Giuseppina BerlingieriStudy Group of Laser and Health Institute, São Paulo, SP, Brazil.
Marcia Christina Camargo Hernandes RamiresStudy Group of Laser and Health Institute, São Paulo, SP, Brazil; Doutor José de Carvalho Florence Hospital, São José dos Campos, SP, Brazil.
Luciana Aparecida de Oliveira P LyraStudy Group of Laser and Health Institute, São Paulo, SP, Brazil; Scholl of Health Science, Universidade Positivo, Curitiba, PR, Brazil.
Inessa Solek TeixeiraStudy Group of Laser and Health Institute, São Paulo, SP, Brazil; Imperial Charity Hospital, Florianópolis, SC, Brazil.
Patrícia Costa OliveiraStudy Group of Laser and Health Institute, São Paulo, SP, Brazil; Instituto Federal do Paraná, Campus Londrina, PR, Brazil.
Ricardo Yudi TatenoGraduate Program in Implantology, University of Santo Amaro, School of Dentistry. São Paulo, SP, Brazil.
Luiz Felipe PalmaGraduate Dentistry Program, Ibirapuera University. São Paulo, SP, Brazil.
Luana CamposStudy Group of Laser and Health Institute, São Paulo, SP, Brazil; Graduate Program in Implantology, University of Santo Amaro, School of Dentistry. São Paulo, SP, Brazil. Electronic address: lucampos@prof.unisa.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Olfactory dysfunction is commonly seen in COVID-19 patients; however, little is known about the pathophysiology and management. The present study aimed to report a series of cases in which three protocols of intranasal photobiomodulation therapy (PBMT) were used for COVID-19-related olfactory dysfunction. Irrespective of the PBMT protocol, olfaction recovery was noted in all cases but with varying degrees of improvement. Although intranasal PBMT seems to be a promising therapeutic modality, more research is needed to better define effectiveness.

Indexed as

COVID-19Low-Level Light TherapyOlfaction DisordersPhotochemotherapyHumansPhotosensitizing AgentsSARS-CoV-2SmellPhotosensitizing AgentsCOVID-19LasersLow-level light therapyOlfactory perceptionPhotobiomodulationSARS-CoV-2Smell

Identifiers

PMID34628071
PMCPMC8496972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.