Observational studyBrazilian journal of anesthesiology (Elsevier)
Investigating preoperative myoglobin level as predictive factor for acute kidney injury following cardiac surgery with cardiopulmonary bypass: a retrospective observational study.
Observational study in Brazilian journal of anesthesiology (Elsevier). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.
- Factors associated with postoperative acute kidney injury in stanford type a aortic dissection in china: a systematic review and meta-analysis.Journal of cardiothoracic surgery · 2026Pooled it
- Biomarkers of postoperative cardiac surgery-associated acute kidney injury: Narrowing the field.JTCVS open · 2025Article
- Risk factor and correlation between postoperative serum myoglobin and acute kidney injury after pulmonary endarterectomy.Journal of thoracic disease · 2024Article
- Dynamic increase in myoglobin level is associated with poor prognosis in critically ill patients: a retrospective cohort study.Frontiers in medicine · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEarly identification of patients at risk of AKI after cardiac surgery is of critical importance for optimizing perioperative management and improving outcomes. This study aimed to identify the association between preoperative myoglobin levels and postoperative acute kidney injury (AKI) in patients undergoing valve surgery or coronary artery bypass graft surgery (CABG) with cardiopulmonary bypass.
methodsThis retrospective study included 293 patients aged over 17 years who underwent valve surgery or CABG with cardiopulmonary bypass. We excluded 87 patients as they met the exclusion criteria. Therefore, 206 patients were included in the final analysis. The patients... demographics as well as intraoperative and postoperative data were collected from electronic medical records. AKI was defined according to the Acute Kidney Injury Network classification system.
resultsOf the 206 patients included in this study, 77 developed AKI. The patients who developed AKI were older, had a history of hypertension, underwent valve surgery with concomitant CABG, had lower preoperative hemoglobin levels, and experienced prolonged extracorporeal circulation (ECC) times. Multivariate logistic regression analysis revealed that preoperative myoglobin levels and ECC time were correlated with the development of AKI. A higher preoperative myoglobin level was an independent risk factor for the development of cardiac surgery-associated AKI.
conclusionsHigher preoperative myoglobin levels may enable physicians to identify patients at risk of developing AKI and optimize management accordingly.
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