Evidence map›Paper›PMID 34627806›Full record

ArticleEuropean journal of pharmacology2021

In vitro characterization of [

Qianwa Liang, Sumit Joshi, Hui Liu, Yanbo Yu, Haiyang Zhao, Tammie L S Benzinger, Joel S Perlmutter, Zhude Tu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. PET Quantification of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  3. Article
  4. No Dopamine Agonist Modulation of Brain [Molecular pharmaceutics · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Qianwa LiangDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Sumit JoshiDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Hui LiuDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Yanbo YuDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Haiyang ZhaoDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Tammie L S BenzingerDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA; Department of Neuroscience, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Joel S PerlmutterDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA; Department of Neuroscience, Washington University School of Medicine, St. Louis, MO, 63110, USA; Department of Neurology, Program in Occupational Therapy, Program in Physical Therapy, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Zhude TuDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, 63110, USA. Electronic address: zhudetu@wustl.edu.
Washington University in St. Louis · US

Funding

PET SPHINGOSINE-1-PHOSPHATE RECEPTOR 1 (S1PR1) RADIOTRACERS FOR MULTIPLE SCLEROSISR01NS103988 · NINDS · WASHINGTON UNIVERSITY · PI Tammie Lee Smith Benzinger, Zhude Tu · 2017 to 2026
$5.3M
PET PROBES FOR IMAGING THE VESICULAR ACETYLCHOLINE TRANSPORTERR01NS075527 · NINDS · WASHINGTON UNIVERSITY · PI TU, ZHUDE · 2011 to 2021
$4.9M
Neuroinflammatory Biomarkers for Nigrostriatal InjuryR01NS107281 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES · 2019 to 2023
$3.3M
Neuroimaging of PDE10AR01NS103957 · NINDS · WASHINGTON UNIVERSITY · PI PERLMUTTER, JOEL SYNES, TU, ZHUDE · 2017 to 2021
$3.1M
DEVELOPMENT OF VESICULAR ACETYLCHOLINE TRANSPORTER IMAGING AGENTS FOR PETR21NS061025 · NINDS · WASHINGTON UNIVERSITY · PI TU, ZHUDE · 2009 to 2010
$628k
NINDS NIH HHS R01 NS075527NINDS NIH HHS R01 NS103957NINDS NIH HHS R01 NS103988NINDS NIH HHS R01 NS107281NINDS NIH HHS R21 NS061025
6 · The paper itself

Abstract

Vesicular acetylcholine transporter plays a crucial role in the cholinergic system, and its alterations is implicated in several neurodegenerative disorders. We recently developed a PET imaging tracer [

Indexed as

BrainVesicular Acetylcholine Transport ProteinsAnimalsBinding, CompetitiveHumansLigandsMalePositron-Emission TomographyRadiopharmaceuticalsRatsRats, Sprague-DawleyTritiumLigandsRadiopharmaceuticalsTritiumVesicular Acetylcholine Transport ProteinsAutoradiographyBinding assayProgressive supranuclear palsyRadioligandStriatumVesicular acetylcholine transporter

Identifiers

PMID34627806
PMCPMC8605764
OpenAlexW3202072646

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.