Evidence map›Paper›PMID 34627691›Full record

ArticleNutrition, metabolism, and cardiovascular diseases : NMCD2021

More frequent olive oil intake is associated with reduced platelet activation in obesity.

Ruina Zhang, Alberto Moscona, Khrystyna Myndzar, Elliot Luttrell-Williams, Sally Vanegas, Melanie R Jay, Karry Calderon, Jeffrey S Berger, Sean P Heffron

Open access · greenAbstract read
In one paragraph

Article in Nutrition, metabolism, and cardiovascular diseases : NMCD, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ruina ZhangDepartment of Medicine, Leon H. Charney Division of Cardiology, NYU Langone Medical Center, NYU School of Medicine, New York, NY, USA.
Alberto MosconaDepartment of Medicine, Leon H. Charney Division of Cardiology, NYU Langone Medical Center, NYU School of Medicine, New York, NY, USA.
Khrystyna MyndzarDepartment of Medicine, Leon H. Charney Division of Cardiology, NYU Langone Medical Center, NYU School of Medicine, New York, NY, USA.
Elliot Luttrell-WilliamsDepartment of Medicine, Leon H. Charney Division of Cardiology, NYU Langone Medical Center, NYU School of Medicine, New York, NY, USA.
Sally VanegasDepartment of Medicine, NYU Langone Medical Center, NYU School of Medicine, New York, NY, USA.
Melanie R JayDepartment of Medicine, NYU Langone Medical Center, NYU School of Medicine, New York, NY, USA.
Karry CalderonDepartment of Medicine, Leon H. Charney Division of Cardiology, NYU Langone Medical Center, NYU School of Medicine, New York, NY, USA.
Jeffrey S BergerDepartment of Medicine, Leon H. Charney Division of Cardiology, NYU Langone Medical Center, NYU School of Medicine, New York, NY, USA; NYU Center for the Prevention of Cardiovascular Disease, NYU Langone Medical Center, NYU School of Medicine, New York, NY, USA; Department of Surgery, NYU Langone Medical Center, NYU School of Medicine, New York, NY, USA.
Sean P HeffronDepartment of Medicine, Leon H. Charney Division of Cardiology, NYU Langone Medical Center, NYU School of Medicine, New York, NY, USA; NYU Center for the Prevention of Cardiovascular Disease, NYU Langone Medical Center, NYU School of Medicine, New York, NY, USA. Electronic address: Heffron@nyulangone.org.
NYU Langone Health · US

Funding

Training Program in Cardiovascular SciencesT32HL098129 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Glenn I Fishman, Ira J Goldberg · 2009 to 2026
$5.9M
Effects of Bariatric Surgery on HDL and Platelet FunctionK23HL135398 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HEFFRON, SEAN PATRICK · 2017 to 2021
$764k
NHLBI NIH HHS K23 HL135398NHLBI NIH HHS T32 HL098129
6 · The paper itself

Abstract

BACKGROUND AND

aimsObesity is an independent risk factor for atherosclerotic cardiovascular disease (CVD), and platelet hyperactivation in obesity may contribute to this association. Olive oil consumption is associated with lower cardiovascular disease (CVD) risk in the general population. However, little is known for individuals with obesity. We investigated whether olive oil intake is associated with platelet activation in obesity. METHODS AND

resultsWe assessed platelet activation (surface P-selectin expression) with and without thrombin exposure and diet composition in 63 patients with severe obesity. Among 63 subjects with obesity, the mean age was 32.2 ± 8.0 years and BMI 44.1 ± 8.5 kg/m

conclusionsMore frequent olive oil intake is associated with reduced thrombin-induced platelet activation in obesity.

Indexed as

ObesityOlive OilPlatelet ActivationAdultHumansOlive OilCardiovascular diseaseObesityOlive oilPlatelet activationP-selectin

Identifiers

PMID34627691
PMCPMC8919933
OpenAlexW3193606213

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.