Evidence map›Paper›PMID 34627568›Full record

Observational studyIndian heart journal

Comparison of multiple risk scores in assessing medium-to long-term clinical outcomes in unstable angina / non-ST-elevation myocardial infarction patients undergoing multi vessel percutaneous coronary intervention: An observational, registry-based study in India.

Gailin Sebastian, Vivek Pillai, Ashraf Manzil, Ramakrishna Damodara, Ish Kalra, Zameel Abdul, Oommen Mathew

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Gailin SebastianDepartment of Cardiology, Government Medical College, Kannur, Kerala, India. Electronic address: gailinbs74@gmail.com.
Vivek PillaiDepartment of Cardiology, Government Medical College, Kannur, Kerala, India. Electronic address: docvivpillai@yahoo.com.
Ashraf ManzilDepartment of Cardiology, Government Medical College, Kannur, Kerala, India. Electronic address: ashsmfz@yahoo.com.
Ramakrishna DamodaraDepartment of Cardiology, Government Medical College, Kannur, Kerala, India. Electronic address: drcdram@yahoo.com.
Ish KalraDepartment of Cardiology, Government Medical College, Kannur, Kerala, India. Electronic address: kalra_ish@yahoo.com.
Zameel AbdulDepartment of Cardiology, Government Medical College, Kannur, Kerala, India. Electronic address: mail2zameel@gmail.com.
Oommen MathewPopulation Research Center, University of Kerala, Thiruvananthapuram, Kerala, India. Electronic address: oommenpm@gmail.com.
Kannur Medical College · INGovernment Medical College · INUniversity of Kerala · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePost-revascularization mortality in multivessel coronary artery disease (MVCAD) has been explored via several risk scores. Here, we assessed and compared various risk scores in predicting medium to long-term clinical outcomes in unstable angina/non-ST-elevation myocardial infarction (UA/NSTEMI) patients with MVCAD undergoing percutaneous coronary intervention (PCI).

methodsWe analyzed a cohort of a tertiary care center registry enrolling patients in South India, Kerala, with MVCAD (N = 200) who had undergone PCI between 2010 and 2018. The outcomes evaluated were all-cause mortality and major adverse cardiac events (MACE). The risk scores assessed included SYNTAX score (SS), residual SYNTAX score (rSS), SYNTAX revascularization index (SRI), age, creatinine, and ejection fraction (ACEF) score, clinical SYNTAX score (cSS), and SYNTAX score II (SSII).

resultsOf the analyzed risk scores, SSII had the best predictive capability with the area under the curve (AUC) of 0.79 in c-statistics, followed by ACEF score and cSS with AUCs of 0.74 and 0.65, respectively for all-cause mortality (p < 0.01). Kaplan-Meier survival curves and multivariate analysis by Cox regression showed SSII with cut-offs of >35.15 and > 29.55 to be the only score associated with higher mortality and MACE, respectively.

conclusionsIn UA/NSTEMI patients with relatively less complex MVCAD treated by PCI, the SSII, ACEF and cSS risk scores could predict the outcomes better. The SSII showed the best predictive performance for all-cause mortality and MACE. Scores based on baseline and residual atherosclerotic burden (SS, rSS, and SRI) performed poorly in predicting the mortality and MACE.

Indexed as

Coronary Artery DiseaseNon-ST Elevated Myocardial InfarctionPercutaneous Coronary InterventionAngina, UnstableCoronary AngiographyHumansPredictive Value of TestsRegistriesRisk AssessmentRisk FactorsTreatment OutcomeMultivessel coronary artery diseaseNon-ST-Elevation myocardial infarctionPercutaneous coronary interventionRisk scoresSYNTAX

Identifiers

PMID34627568
PMCPMC8514402
OpenAlexW3188658742

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.