Evidence map›Paper›PMID 34627473›Full record

ArticleThe Lancet. Planetary health2021

Long-term effect of exposure to lower concentrations of air pollution on mortality among US Medicare participants and vulnerable subgroups: a doubly-robust approach.

Mahdieh Danesh Yazdi, Yan Wang, Qian Di, Weeberb J Requia, Yaguang Wei, Liuhua Shi, Matthew Benjamin Sabath, Francesca Dominici, Brent Coull, John S Evans and 2 more

Abstract read
In one paragraph

Article in The Lancet. Planetary health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

  1. Article
  2. Article
  3. Atmospheric stressors and kidney diseases.Nature reviews. Nephrology · 2026
    Review
  4. Impact of PMJournal of environmental health science & engineering · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Wildfire smoke PMScience advances · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. The Impact of Air Quality on Patient Mortality: A National Study.International journal of environmental research and public health · 2025
    Article
  16. Article
  17. Estimates of submicron particulate matter (PMThe Lancet. Planetary health · 2025
    Article
  18. Article
  19. Daily Land Surface Temperature Reconstruction in Landsat Cross-Track Areas Using Deep Ensemble Learning With Uncertainty Quantification.IEEE transactions on geoscience and remote sensing : a publication of the IEEE Geoscience and Remote Sensing Society · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mahdieh Danesh YazdiDepartment of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA.
Yan WangDepartment of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA; Department of Biostatistics, Harvard TH Chan School of Public Health, Boston, MA, USA.
Qian DiDepartment of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA; Vanke School of Public Health, Tsinghua University, Beijing, China.
Weeberb J RequiaDepartment of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA; School of Public Policy and Government, Fundação Getúlio Vargas, Brasília, Brazil.
Yaguang WeiDepartment of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA.
Liuhua ShiDepartment of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA; Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Matthew Benjamin SabathDepartment of Biostatistics, Harvard TH Chan School of Public Health, Boston, MA, USA.
Francesca DominiciDepartment of Biostatistics, Harvard TH Chan School of Public Health, Boston, MA, USA.
Brent CoullDepartment of Biostatistics, Harvard TH Chan School of Public Health, Boston, MA, USA.
John S EvansDepartment of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA.
Petros KoutrakisDepartment of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA.
Joel D SchwartzDepartment of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA, USA; Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA. Electronic address: jschwrtz@hsph.harvard.edu.

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI Carmen Joseph Marsit · 2013 to 2026
$22.6M
Air Pollution and Alzheimer's Disease and Related Dementias: A National StudyR01AG074357 · NIA · EMORY UNIVERSITY · PI STEENLAND, NELSON K · 2021 to 2025
$3.4M
EPA R835872NIA NIH HHS R01 AG074357NIEHS NIH HHS P30 ES000002NIEHS NIH HHS P30 ES019776
6 · The paper itself

Abstract

backgroundLong-term exposure to air pollution has been linked with an increase in risk of mortality. Whether existing US Environmental Protection Agency standards are sufficient to protect health is unclear. Our study aimed to examine the relationship between exposure to lower concentrations of air pollution and the risk of mortality.

methodsOur nationwide cohort study investigated the effect of annual average exposure to air pollutants on all-cause mortality among Medicare enrolees from the beginning of 2000 to the end of 2016. Patients entered the cohort in the month of January following enrolment and were followed up until the end of the study period in 2016 or death. We restricted our analyses to participants who had only been exposed to lower concentrations of pollutants over the study period, specifically particulate matter less than 2·5 μg/m

findingsWe found an increased risk of mortality with all three pollutants. Each 1 μg/m

fundingThe US Environmental Protection Agency, National Institute of Environmental Health Services, and Health Effects Institute.

Indexed as

Air PollutionEnvironmental ExposureAgedCohort StudiesHumansMedicareParticulate MatterUnited StatesParticulate Matter

Identifiers

PMID34627473
PMCPMC8525655

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.