ArticleJournal of physiological anthropology2021
Association between thyroid-stimulating hormone (TSH) and proteinuria in relation to thyroid cyst in a euthyroid general population.
Article in Journal of physiological anthropology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 5 citations in OpenAlex.
- Chronic kidney disease as a potential risk factor for pituitary hormone dysregulation: a review of the underlying mechanisms.Molecular biology reports · 2026Review
- Subclinical hypothyroidism and height loss in relation to the status of thyroid cysts: a prospective study.Environmental health and preventive medicine · 2026Article
- Association between bedtime snacking and subclinical hypothyroidism.Environmental health and preventive medicine · 2026Article
- Subclinical hypothyroidism and height loss according to free thyroxine levels: a prospective study.Environmental health and preventive medicine · 2025Article
- Assessment of the renal function of patients with anorexia nervosa.BioPsychoSocial medicine · 2024Article
- Correlation of serum thyrotropin and thyroid hormone levels with diabetic kidney disease: a cross-sectional study.BMC endocrine disorders · 2024Article
- Serum Concentration of Growth Differentiation Factor 15 and Atherosclerosis among General Older Japanese Individuals with Normal Weight.Biomedicines · 2023Article
- Height and Active Arterial Wall Thickening in Relation to Thyroid Cysts Status among Elderly Japanese: A Prospective Study.Biology · 2022Article
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHigh normal levels of thyroid-stimulating hormone (TSH) have been reported to be associated with chronic kidney disease (CKD) among euthyroid individuals. However, there has been only limited research on the association between TSH and proteinuria, a major risk factor for the progression of renal disease.
methodsA cross-sectional study of 1595 euthyroid individuals was conducted. All participants were within the normal range for free triiodothyronine (T3), free thyroxine (T4), and TSH. Analyses were stratified by thyroid cyst status to test the hypothesis that the absence of thyroid cysts, an indicator of latent thyroid damage, is associated with declining ability to synthesis thyroid hormone.
resultsFor participants with thyroid cysts, a significant inverse association between TSH and proteinuria was observed (adjusted odds ratio (95% confidence intervals) of log-transformed TSH for proteinuria 0.40 (0.18, 0.89)). In participants without thyroid cysts, a significant positive association between those two factors was observed (2.06 (1.09, 3.90)).
conclusionsAmong euthyroid individuals in the general population, being in the normal range of TSH was found to have an ambivalent association with proteinuria. Thyroid cyst status could be an effect modifier for those associations.
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