Evidence map›Paper›PMID 34627366›Full record

ArticleAntimicrobial resistance and infection control2021

Overuse of antibiotics in maternity and neonatal wards, a descriptive report from public hospitals in Dar es Salaam, Tanzania.

Mwaka A Kakolwa, Susannah L Woodd, Alexander M Aiken, Fatuma Manzi, Giorgia Gon, Wendy J Graham, Abdunoor M Kabanywanyi

Open access · goldAbstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Mwaka A KakolwaIfakara Health Institute, PO Box 78373, Dar es Salaam, Tanzania. mkakolwa@ihi.or.tz.ORCID 0000-0002-0373-390X
Susannah L WooddLondon School of Hygiene and Tropical Medicine, Faculty of Epidemiology and Population Health, Keppel Street, London, UK.
Alexander M AikenLondon School of Hygiene and Tropical Medicine, Faculty of Epidemiology and Population Health, Keppel Street, London, UK.
Fatuma ManziIfakara Health Institute, PO Box 78373, Dar es Salaam, Tanzania.
Giorgia GonLondon School of Hygiene and Tropical Medicine, Faculty of Epidemiology and Population Health, Keppel Street, London, UK.
Wendy J GrahamLondon School of Hygiene and Tropical Medicine, Faculty of Epidemiology and Population Health, Keppel Street, London, UK.
Abdunoor M KabanywanyiIfakara Health Institute, PO Box 78373, Dar es Salaam, Tanzania.
University of London · GBIfakara Health Institute · TZ

Funding

Medical Research Council MR/R019274/1UK Joint Global Health Trials (Wellcome, MRC, DFID and DOH) MR/R019274/1Wellcome Trust
6 · The paper itself

Abstract

backgroundOveruse of antibiotics is a major challenge and undermines measures to control drug resistance worldwide. Postnatal women and newborns are at risk of infections and are often prescribed prophylactic antibiotics although there is no evidence to support their universal use in either group.

methodsWe performed point prevalence surveys in three hospitals in Dar es Salaam, Tanzania, in 2018 to collect descriptive data on antibiotic use and infections, in maternity and neonatal wards.

resultsPrescribing of antibiotics was high in all three hospitals ranging from 90% (43/48) to 100% (34/34) in women after cesarean section, from 1.4% (1/73) to 63% (30/48) in women after vaginal delivery, and from 89% (76/85) to 100% (77/77) in neonates. The most common reason for prescribing antibiotics was medical prophylaxis in both maternity and neonatal wards.

conclusionsWe observed substantial overuse of antibiotics in postnatal women and newborns. This calls for urgent antibiotic stewardship programs in Tanzanian hospitals to curb this inappropriate use and limit the spread of antimicrobial resistance.

Indexed as

Anti-Bacterial AgentsDelivery RoomsFemaleHospitals, PublicHumansInfant, NewbornInfant, Newborn, DiseasesNurseries, HospitalPostnatal CarePregnancyPregnancy Complications, InfectiousPrescription Drug OveruseSurveys and QuestionnairesTanzaniaAnti-Bacterial AgentsAntibioticsMaternalMaternityNeonatalStewardshipTanzania

Identifiers

PMID34627366
PMCPMC8502304
OpenAlexW3183432502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.