ArticleReproductive biology and endocrinology : RB&E2021
Effect of endometrial thickness changes on clinical pregnancy rates after progesterone administration in a single frozen-thawed euploid blastocyst transfer cycle using natural cycles with luteal support for PGT-SR- and PGT-M-assisted reproduction: a retrospective cohort study.
Article in Reproductive biology and endocrinology : RB&E, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Can endometrial compaction predict live birth rates in assisted reproductive technology cycles? A systematic review and meta-analysis.Journal of assisted reproduction and genetics · 2023Pooled it
- Does endometrial compaction before embryo transfer affect pregnancy outcomes? a systematic review and meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Development and internal temporal validation of an explainable XGBoost model for predicting clinical pregnancy after frozen embryo transfer.Frontiers in endocrinology · 2026Article
- A New Method of Assessing Endometrial Compaction as an Indicator of Endometrial Receptivity for Predicting Reproductive Success.Journal of clinical medicine · 2025Article
- Machine learning prediction of clinical pregnancy in endometriosis patients following fresh IVF/ICSI-ET.European journal of medical research · 2025Article
- Value analysis of serum β -HCG, AMH, and P/EPakistan journal of medical sciences · 2025Article
- Endometrial compaction shows no association with improved pregnancy outcomes in hormonal replacement frozen-thawed embryo transfer: an analysis of over 16 000 cases.Human reproduction open · 2025Article
- Endometrial compaction in patients with chronic endometritis does not predict pregnancy outcomes: a retrospective study.Frontiers in endocrinology · 2025Article
- Endometrial Thickness Change in Response to Progesterone is Associated with Ongoing Pregnancy Rate in Women with Treated Intrauterine Adhesion - A Prospective Cohort Study.International journal of women's health · 2025Article
- No improvement in pregnancy and perinatal outcomes with combined luteal support in modified natural cycle frozen embryo transfer.Frontiers in endocrinology · 2024Article
- Endometrial compaction to predict pregnancy outcomes in patients undergoing assisted reproductive technologies: a systematic review and meta-analysis.Human reproduction open · 2024Article
- Endometrial compaction is associated with the outcome of artificial frozen-thawed embryo transfer cycles: a retrospective cohort study.Journal of assisted reproduction and genetics · 2023Article
- Impact of endometrial compaction on reproductive outcomes after cryotransfer of euploid embryos in a modified natural cycle: protocol for a prospective cohort study.Frontiers in endocrinology · 2023Article
- Endometrial receptivity change: ultrasound evaluation on ovulation day and transplantation day during the natural frozen embryo transfer cycle.Frontiers in endocrinology · 2023Article
- Endometrial thickness and early pregnancy complications after frozen-thawed embryo transfers.Frontiers in endocrinology · 2023Article
- Endometrial compaction after human chorionic gonadotrophin administration reduces ectopic pregnancy rate following fresh embryo transfer in vitro fertilization/intracytoplasmic sperm injection cycles in patients with non-thin endometrium: a retrospective cohort study.Reproductive biology and endocrinology : RB&E · 2022Article
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Authors and funding
10 authors.
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Abstract
backgroundTo investigate whether the endometrial thickness change ratio from the progesterone administration day to the blastocyst transfer day is associated with pregnancy outcomes in a single frozen-thawed euploid blastocyst transfer cycle.
methodsAll patients used natural cycles with luteal support for endometrial preparation and selected a single euploid blastocyst for transfer after a biopsy for preimplantation genetic testing. The endometrial thickness was measured by transvaginal ultrasound on the progesterone administration day and the transfer day, the change in endometrial thickness was measured, and the endometrial thickness change ratio was calculated. According to the change rate of endometrial thickness, the patients were divided into three groups: the endometrial thickness compaction group, endometrial thickness non-change group and endometrial thickness expansion group. Among them, the endometrial thickness non-change and expansion groups were combined into the endometrial thickness noncompaction group.
resultsUltrasound images of the endometrium in 219 frozen-thawed euploid blastocyst transfer cycles were evaluated. The clinical pregnancy rate increased with the increase in endometrial thickness change ratio, while the miscarriage rate and live birth rate were comparable among the groups. The multiple logistic regression results showed that in the fully adjusted model a higher endometrial thickness change ratio (per 10%) was associated with a higher clinical pregnancy rate (adjusted odds ratio [aOR] 1.29; 95% confidence interval [CI], 1.01-1.64; P = .040). Similarly, when the patients were divided into three groups according to the change rate of endometrial thickness, the endometrial thickness noncompaction group had a significant positive effect on the clinical pregnancy rate compared with the endometrial thickness compaction group after adjusting for all covariates.
conclusionsIn frozen-thawed euploid blastocyst transfer cycles in which the endometrium was prepared by natural cycles with luteal support, the clinical pregnancy rate was higher in cycles without endometrial compaction after progesterone administration.
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