ArticleBMC musculoskeletal disorders2021
Influence of the appendicular skeletal muscle mass index on the bone mineral density of postmenopausal women.
Article in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Associations between body composition and bone loss in early postmenopausal women.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026Article
- Mediating Role of Muscle Mass in the Relationship Between Physical Activity and Bone Mass in Female University Students in China.PPAR research · 2026Article
- Association between appendicular skeletal muscle index and bone turnover markers and bone mineral density in postmenopausal osteoporotic women.Archives of osteoporosis · 2025Article
- Association between sarcopenia, its components, and osteoporosis in the FRISBEE cohort.BMC musculoskeletal disorders · 2025Article
- Muscle-Bone Relationship: Positive Association Between Appendicular Skeletal Muscle Mass and Bone Microarchitecture in Postmenopausal Women.Journal of nutrition and metabolism · 2025Article
- Correlation of body compositions and bone mineral density in postmenopausal women with different body mass index.Frontiers in endocrinology · 2025Article
- Article
- Skeletal muscle mass obtained by anthropometric equation and presence of sarcopenia in postmenopausal women.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2024Observational
- Low appendicular skeletal muscle mass index is associated with the anthropometric variables of post-menopausal women.BMC geriatrics · 2022Observational
- Dietary consumption of selenium inversely associated with osteoporosis in postmenopausal women.Frontiers in nutrition · 2022Article
- The inverse relationship between fatness and bone mineral content is mediated by the adolescent appendicular skeletal muscle mass index: The Cogni-Action Project.Frontiers in nutrition · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe appendicular skeletal muscle mass index (ASMI) is an important risk indicator for osteoporosis because of the anatomical proximity and metabolic connection between muscle and bone mass. The present study investigated the relationship between ASMI and the bone mineral density (BMD) categories of postmenopausal women.
methodsIn this cross-sectional study with a probabilistic sample, sociodemographic, lifestyle, menopause time, anthropometric, and physical activity variables were collected. ASMI and BMD were assessed by dual-energy X-ray absorptiometry (DXA). Participants were grouped according to BMD values into normal density, osteopenia, and osteoporosis. Multivariate logistic regression models were applied to verify the influence of ASMI on BMD. Data were analyzed using the SPSS statistical software, version 22. The significance level for all tests was set at 5%.
resultsOf the 114 women analyzed, most were between 60 and 69.9 years of age (62.3%), on menopause for ≤19.0 (51.8%), self-declared brown race/color (49.1%), had < 4 years of education (41.2%), never smoked (69.0%) or drank alcohol (62.8%). Of these, 52.6% were classified as sufficiently active and 52.2% had regular sun exposure. Women with osteoporosis were older (p = 0.035), on menopause for a longer time (p = 0.011), underweight (p = 0.004), had adequate waist circumference (p = 0.017), and low ASMI values (p = 0.002). There was an association between the 1st tertile of ASMI and osteoporosis. However, after adjustments for age, race/color, and body mass index, the strength of association between BMD and ASMI was not maintained.
conclusionsASMI was not associated with the BMD of the postmenopausal women evaluated. Total body and muscle mass, in addition to bone mass, should be monitored during menopause treatment. Longitudinal studies must be conducted to elucidate the mechanisms and gaps in this relationship.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.