ArticleBMC public health2021
Spatio-temporal variation in tuberculosis incidence and risk factors for the disease in a region of unbalanced socio-economic development.
Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
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26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Acceptance of preventive therapy for latent tuberculosis infection in Chinese children and adolescents: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Challenge of ending TB in China: tuberculosis control in primary healthcare sectors under integrated TB control model-a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Geo-spatial high-risk clusters of Tuberculosis in the global general population: a systematic review.BMC public health · 2023Pooled it
- Article
- The impact of modifiable social determinants on tuberculosis incidence: insights from a Bayesian spatiotemporal and counterfactual analysis.BMC public health · 2026Article
- Age-period-cohort analysis of pulmonary tuberculosis epidemiological trends from 2005 to 2024 and forecasts for 2035 in Sichuan Province, China.Frontiers in public health · 2026Article
- Geospatial analysis of shared risks for tuberculosis transmission in an urban cohort.Scientific reports · 2025Article
- Rapid discrimination ofBMJ health & care informatics · 2025Article
- Area-level socioeconomic variables associated with territorial disparities in tuberculosis notification rates in metropolitan France: a Bayesian ecological analysis.Infectious diseases of poverty · 2025Article
- Spatiotemporal evolution and impacts of environment on scrub typhus in northern China, 2006-2019.Journal of global health · 2025Article
- Observational
- Effect of population aging on pulmonary tuberculosis burden in Zhejiang Province, China: a population-based study.Frontiers in public health · 2025Article
- Cross-District Transmission of Tuberculosis in a High-Mobility City in China: Implications for Regional Collaboration in Infectious Disease Control.Infection and drug resistance · 2025Article
- Epidemiological changes in tuberculosis and genotyping characteristics ofFrontiers in microbiology · 2025Review
- Analysis of the epidemiological characteristics and influencing factors of tuberculosis among students in a large province of China, 2008-2018.Scientific reports · 2024Article
- A Profile of Drug-Resistant Mutations inIndian journal of microbiology · 2024Article
- Toward tuberculosis elimination by understanding epidemiologic characteristics and risk factors in Hainan Province, China.Infectious diseases of poverty · 2024Article
- Spatial pattern of isoniazid-resistant tuberculosis and its associated factors among a population with migrants in China: a retrospective population-based study.Frontiers in public health · 2024Article
- Spatiotemporal Distribution of Tuberculosis in the Oromia Region of Ethiopia: A Hotspot Analysis.Tropical medicine and infectious disease · 2023Article
- Spatial analysis of overweight prevalence in China: exploring the association with air pollution.BMC public health · 2023Article
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8 authors at 5 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious research pointed to a close relationship between the incidence of tuberculosis (TB) in aging populations and socio-economic conditions, however there has been lack of studies focused on a region of unbalanced socio-economic development. The aim of this paper is to explore the spatio-temporal variation in TB incidence and examine risk determinants of the disease among aging populations in a typical region.
methodsData on TB-registered cases between 2009 and 2014, in addition to social-economic factors, were collected for each district/county in Beijing, Tianjin and Hebei, a region characterized by an aging population and disparities in social-economic development. A Bayesian space-time hierarchy model (BSTHM) was used to reveal spatio-temporal variation in the incidence of TB among the elderly in this region between 2009 to 2014. GeoDetector was applied to measure the determinant power (q statistic) of risk factors for TB among the elderly.
resultsThe incidence of TB among the elderly exhibited geographical spatial heterogeneity, with a higher incidence in underdeveloped rural areas compared with that in urban areas. Hotspots of TB incidence risk among the elderly were mostly located in north-eastern and southern areas in the study region, far from metropolitan areas. Areas with low risk were distributed mainly in the Beijing-Tianjin metropolitan areas. Social-economic factors had a non-linear influence on elderly TB incidence, with the dominant factors among rural populations being income (q = 0.20) and medical conditions (q = 0.17). These factors had a non-linear interactive effect on the incidence of TB among the elderly, with medical conditions and the level of economic development having the strongest effect (q = 0.54).
conclusionsThe findings explain spatio-temporal variation in TB incidence and risk determinants of elderly TB in the presence of disparities in social-economic development. High-risk zones were located mainly in rural areas, far from metropolitan centres. Medical conditions and the economic development level were significantly associated with elderly TB incidence, and these factors had a non-linear interactive effect on elderly TB incidence. The findings can help to optimize the allocation of health resources and to control TB transmission in the aging population in this region.
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