Evidence map›Paper›PMID 34627184›Full record

ArticleBMC pregnancy and childbirth2021

Fetal growth velocity references from a Chinese population-based fetal growth study.

Tianchen Wu, Xiaoli Gong, Yangyu Zhao, Lizhen Zhang, Yiping You, Hongwei Wei, Xifang Zuo, Ying Zhou, Xinli Xing, Zhaoyan Meng and 14 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Establishing Chinese Fetal Growth Standards: Why and How.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Tianchen WuDepartment of Maternal and Child Health, School of Public Health, Peking University, Beijing, 100191, China.
Xiaoli GongDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.
Yangyu ZhaoDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.
Lizhen ZhangDepartment of Obstetrics and Gynecology, Maternal and Child Health Hospital of Qinhuangdao, Qinhuangdao, 066000, China.
Yiping YouDepartment of Obstetrics, Maternal and Child Health Hospital of Hunan, Changsha, 410007, China.
Hongwei WeiDepartment of Obstetrics, Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530000, China.
Xifang ZuoDepartment of Obstetrics, Tongzhou Maternal and Child Health Hospital of Beijing, Beijing, 101100, China.
Ying ZhouDepartment of Obstetrics and Gynecology, the First Affiliated Hospital of Xiamen University, Xiamen, 361003, China.
Xinli XingMaternal and Child Health Hospital of Dongchangfu District, Liaocheng, 252004, China.
Zhaoyan MengDepartment of Obstetrics, Gansu Maternal and Child Health Hospital, Lanzhou, 730050, China.
Qi LvDepartment of Obstetrics and Gynecology, Changchun Obstetrics-Gynecology Hospital, Changchun, 130042, China.
Zhaodong LiuFujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fu Zhou, 350122, China.
Jian ZhangDepartment of Function, Maternal and Child Health Hospital of Shijiazhuang, Shijiazhuang, 050051, China.
Liyan HuChildren's Hospital of Shanxi, Women Health Center of Shanxi, Taiyuan, 030013, China.
Junnan LiDepartment of Obstetrics, the First Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Li LiDepartment of Obstetrics, Zhengzhou Central Hospital, Zhengzhou, 450007, China.
Chulin ChenDepartment of Obstetrics, Maternal and Child Health Hospital of Changzhi, Changzhi, 046011, China.
Chunyan LiuDepartment of Obstetrics, Maternity and Infant Hospital of Shenyang, Shenyang, 110014, China.
Guoqiang SunDepartment of Obstetrics, Hubei Maternal and Child Health Hospital, Wuhan, 430070, China.
Aiju LiuDepartment of Obstetrics, Inner Mongolia Maternal and Child Health Hospital, Hohhot, 010060, China.
Jingsi ChenDepartment of Prenatal Diagnosis, the Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510150, China.
Yuan LvShengjing Hospital Affiliated to China Medical University, Shenyang, 117004, China.
Xiaoli WangDepartment of Maternal and Child Health, School of Public Health, Peking University, Beijing, 100191, China. xlwang@bjmu.edu.cn.
Yuan WeiDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China. weiyuanbysy@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFetal growth velocity standards have yet to be established for the Chinese population. This study aimed to establish such standards suitable for the Chinese population.

methodsWe performed a multicenter, population-based longitudinal cohort study including 9075 low-risk singleton pregnant women. Data were collected from the clinical records of 24 hospitals in 18 provinces of China. Demographic characteristics, reproductive history, fetal ultrasound measurements, and perinatal outcome data were collected. The fetal ultrasound measurements included biparietal diameter (BPD), abdominal circumference (AC), head circumference (HC), and femur diaphysis length (FDL). We used linear mixed models with cubic splines to model the trajectory of four ultrasound parameters and estimate fetal weight. Fetal growth velocity was determined by calculating the first derivative of fetal size curves. We also used logistic regression to estimate the association between fetal growth velocities in the bottom 10th percentile and adverse perinatal outcomes.

resultsFetal growth velocity was not consistent over time or among individuals. The estimated fetal weight (EFW) steadily increased beginning at 12 gestational weeks and peaked at 35 gestational weeks. The maximum velocity was 211.71 g/week, and there was a steady decrease in velocity from 35 to 40 gestational weeks. The four ultrasound measurements increased in the early second trimester; BPD and HC peaked at 13 gestational weeks, AC at 14 gestational weeks, and FDL at 15 gestational weeks. BPD and HC also increased from 19 to 24 and 19 to 21 gestational weeks, respectively. EFW velocity in the bottom 10th percentile indicated higher risks of neonatal complications (odds ratio [OR] = 2.23, 95% confidence interval [CI]: 1.79-2.78) and preterm birth < 37 weeks (OR = 3.68, 95% CI: 2.64-5.14). Sensitivity analyses showed that EFW velocity in the bottom 10th percentile was significantly associated with more adverse pregnancy outcomes for appropriate-for-gestational age neonates.

conclusionsWe established fetal growth velocity curves for the Chinese population based on real-world clinical data. Our findings demonstrated that Chinese fetal growth patterns are somewhat different from those of other populations. Fetal growth velocity could provide more information to understand the risk of adverse perinatal outcomes, especially for appropriate-for-gestational age neonates.

Indexed as

Fetal DevelopmentAdultBirth WeightChinaCohort StudiesFemaleFetal Growth RetardationFetal WeightFetusGestational AgeGrowth ChartsHumansInfant, NewbornLongitudinal StudiesPregnancyPregnancy OutcomeEstimated fetal weightFetal growthFetal growth velocityLongitudinal study

Identifiers

PMID34627184
PMCPMC8501691

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