ArticleJournal of infection and public health2021
Factors associated with poor outcomes among hospitalized patients with COVID-19: Experience from a MERS-CoV referral hospital.
Article in Journal of infection and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Orthopaedic, trauma surgery, and Covid-2019 pandemic: clinical panorama and future prospective in Europe.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Pooled it
- Artificial intelligence-based model for COVID-19 prognosis incorporating chest radiographs and clinical data; a retrospective model development and validation study.The British journal of radiology · 2022Trial
- The Impact of Viral Load on the Severity and Outcome Among Patients With COVID-19: A Cross-Sectional Study.Cureus · 2024Article
- Effectiveness of COVID-19 vaccines against ICU admission during Omicron surge in Saudi Arabia: a nationwide retrospective cohort study.BMC infectious diseases · 2023Article
- Carbapenem use correlates with percentage of patients with COVID-19 in intensive care units.Infection · 2023Article
- Deep Learning-Based Time-to-Death Prediction Model for COVID-19 Patients Using Clinical Data and Chest Radiographs.Journal of digital imaging · 2023Article
- Post-COVID-19 syndrome: assessment of short- and long-term post-recovery symptoms in recovered cases in Saudi Arabia.Infection · 2022Article
- COVID-19 vaccine had a significant positive impact on patients with SARS-COV-2 during the third (Omicron) wave in Saudi Arabia.Journal of infection and public health · 2022Article
- Comparison of Hospital Readmission and Mortality between COVID-19 and Pneumonia Patients.Journal of clinical medicine · 2022Article
- Co-Management of COVID-19 and Heart Failure During the COVID-19 Pandemic: Lessons Learned.Reviews in cardiovascular medicine · 2022Review
- Predictors of Poor Outcome among Critically Ill COVID-19 Patients: A Nationally Representative Sample of the Saudi Arabian Population.Journal of clinical medicine · 2022Article
- Clinical Presentation and Outcome of Hospitalized Patients With COVID-19 in the First and Second Waves in Saudi Arabia.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022Article
- Prevalence of secondary infections and association with mortality rates of hospitalized COVID-19 patients.Annals of Saudi medicineArticle
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12 authors.
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Abstract
backgroundCoronavirus disease 2019 (COVID-19) has resulted in millions of deaths, including more than 6000 deaths in the Kingdom of Saudi Arabia (KSA). Identifying key predictors of intensive care unit (ICU) admission and mortality among infected cases would help in identifying individuals at risk to optimize their care. We aimed to determine factors of poor outcomes in hospitalized patients with COVID-19 in a large academic hospital in Riyadh, KSA that serves as a Middle East Respiratory Syndrome coronavirus (MERS-CoV) referral center.
methodsThis is a single-center retrospective cohort study of hospitalized patients between March 15 and August 31, 2020. The study was conducted at King Saud University Medical City (KSUMC). COVID-19 infection was confirmed using real-time reverse transcriptase polymerase chain reaction (RT-PCR) for SARS-COV-2. Demographic data, clinical characteristics, laboratory, radiological features, and length of hospital stay were obtained. Poor outcomes were, admission to ICU, need for invasive mechanical ventilation (IMV), and in-hospital all-cause mortality.
resultsOut of 16,947 individuals tested in KSUMC, 3480 (20.5%) tested positive for SARS-CoV-2 and of those 743 patients (21%) were hospitalized. There were 62% males, 77% were younger than 65 years. Of all cases, 204 patients (28%) required ICU admission, 104 (14%) required IMV, and 117 (16%) died in hospital. In bivariate analysis, multiple factors were associated with mortality among COVID-19 patients. Further multivariate analysis revealed the following factors were associated with mortality: respiratory rate more than 24/min and systolic blood pressure <90 mmHg in the first 24h of presentation, lymphocyte count <1 × 10
conclusionVariable factors were identified as predictors of different outcomes among COVID-19 patients. The only predictor of IMV was a low initial Ct values of SARS-CoV-2 PCR. The presence of tachypnea, hypotension, lymphopenia, and elevated AST in the first 48h of presentation were independently associated with mortality. This study provides possible independent predictors of mortality and invasive mechanical ventilation. The data may be helpful in the early identification of high-risk COVID-19 patients in areas endemic with MERS-CoV.
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