Evidence map›Paper›PMID 34626856›Full record

ArticleThe journal of allergy and clinical immunology. In practice2022

Neighborhoods, Caregiver Stress, and Children's Asthma Symptoms.

Erin M Rodríguez, Craig Evan Pollack, Corinne Keet, Roger D Peng, Susan Balcer-Whaley, James Custer, Pete Cimbolic, Elizabeth C Matsui

Open access · greenAbstract read
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Asthma and Sleep-disordered Breathing Overlap in School-aged Children.Annals of the American Thoracic Society · 2024
    Article
  7. Review
  8. Asthma and Chronic Obstructive Pulmonary Disease.Clinics in chest medicine · 2023
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Erin M RodríguezDepartment of Educational Psychology, University of Texas at Austin, Austin, Texas.
Craig Evan PollackJohn Hopkins University, Baltimore, Md.
Corinne KeetJohn Hopkins University, Baltimore, Md.
Roger D PengJohn Hopkins University, Baltimore, Md.
Susan Balcer-WhaleyJohn Hopkins University, Baltimore, Md.
James CusterDell Medical School, University of Texas at Austin, Austin, Texas.
Pete CimbolicBaltimore Regional Housing Partnership, Baltimore, Md.
Elizabeth C MatsuiDell Medical School, University of Texas at Austin, Austin, Texas. Electronic address: elizabeth.matsui@austin.utexas.edu.
The University of Texas at Austin · US

Funding

Mouse Allergen and Asthma Intervention TrialU01AI083238 · NIAID · JOHNS HOPKINS UNIVERSITY · PI MATSUI, ELIZABETH C. · 2010 to 2014
$7.9M
The effect of a housing mobility program on environmental exposures and asthma morbidity among low-income minority childrenR01ES026170 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI KEET, CORINNE, MATSUI, ELIZABETH C. · 2016 to 2025
$6.8M
Environmental Control as Add-on Therapy in Urban Children with AsthmaR01ES023447 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI MATSUI, ELIZABETH C. · 2014 to 2018
$3.4M
Mentoring in Patient-Oriented Research on Asthma and the Indoor EnvironmentK24AI114769 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI MATSUI, ELIZABETH C. · 2015 to 2023
$1.6M
NIAID NIH HHS K24 AI114769NIAID NIH HHS U01 AI083238NIEHS NIH HHS R01 ES023447NIEHS NIH HHS R01 ES026170
6 · The paper itself

Abstract

backgroundNeighborhood and caregiver characteristics have each been linked to children's asthma outcomes, but less is known about how caregiver psychosocial functioning may explain the link between neighborhood characteristics and asthma outcomes.

objectiveTo examine associations between neighborhood safety, caregiver stress and depressive symptoms, and children's asthma outcomes, and to evaluate whether caregiver stress and depressive symptoms mediate the relationship between neighborhood safety and asthma outcomes.

methodsWe analyzed baseline data from a prospective cohort study of the effects of a housing mobility program on children's asthma-related outcomes. Age- and sex-adjusted models evaluated associations of neighborhood safety, and caregiver stress and depressive symptoms, with children's asthma symptoms and exacerbations.

resultsParticipants were 140 low-income children with persistent asthma (98% Black participants; 53% males; mean age, 9.0 years) with an average of 7.1 ± 5.3 maximum symptom days per 2 weeks. Lower neighborhood safety, and higher caregiver stress and depressive symptoms, were associated with higher asthma symptoms, but not exacerbations, in adjusted models (eg, for neighborhood safety, maximum symptom days: odds ratio, 1.41; 95% CI, 1.07-1.88; for caregiver stress, maximum symptom days: odds ratio, 1.08; 95% CI, 1.01-1.15; for depressive symptoms, maximum symptom days: odds ratio, 1.05; 95% CI, 1.00-1.11). Exploratory analyses suggested that caregiver stress partially mediated associations between neighborhood safety and asthma symptoms for children in unsafe neighborhoods.

conclusionsNeighborhood safety was associated with children's asthma symptoms independent from caregiver stress and depressive symptoms, although for children in unsafe neighborhoods, caregiver stress may partially mediate this association. Findings suggest the importance of targeting multiple systems to improve children's asthma outcomes.

Indexed as

AsthmaCaregiversChildFemaleHumansMalePovertyProspective StudiesResidence CharacteristicsAsthmaChildDepressionNeighborhoodStressUrban

Identifiers

PMID34626856
PMCPMC8986889
OpenAlexW3203918803

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.