Evidence map›Paper›PMID 34626494›Full record

ReviewActa paediatrica (Oslo, Norway : 1992)2022

Farming lifestyle and human milk: Modulation of the infant microbiome and protection against allergy.

Courtney M Jackson, Mustafa M Mahmood, Kirsi M Järvinen

Open access · greenAbstract readReview
In one paragraph

Review in Acta paediatrica (Oslo, Norway : 1992), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Intestinal Colonization WithFrontiers in pediatrics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Courtney M JacksonSchool of Medicine and Dentistry, Department of Pediatrics, Division of Allergy and Immunology, University of Rochester, Rochester, NY, USA.ORCID https://orcid.org/0000-0002-1777-688X
Mustafa M MahmoodSchool of Medicine and Dentistry, Department of Pediatrics, Division of Allergy and Immunology, University of Rochester, Rochester, NY, USA.
Kirsi M JärvinenSchool of Medicine and Dentistry, Department of Pediatrics, Division of Allergy and Immunology, University of Rochester, Rochester, NY, USA.
University of Rochester · US

Funding

VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI Sally W Thurston · 1985 to 2026
$42.8M
MULTIDISCIPLINARY TRAINING IN PULMONARY RESEARCHT32HL066988 · NHLBI · UNIVERSITY OF ROCHESTER · PI GEORAS, STEVE N, O'REILLY, MICHAEL A · 2001 to 2021
$8.1M
Impact of Maternal Diet and Supplements on Breast Milk CompositionU01AI131344 · NIAID · UNIVERSITY OF ROCHESTER · PI JARVINEN-SEPPO, KIRSI · 2017 to 2021
$3.0M
Impact of Breast Milk on Infant Gut MicrobiomeR21TR002516 · NCATS · UNIVERSITY OF ROCHESTER · PI JARVINEN-SEPPO, KIRSI, LOONEY, RICHARD JOHN · 2018 to 2019
$462k
NCATS NIH HHS R21 TR002516NHLBI NIH HHS T32 HL066988NIAID NIH HHS U01 AI131344NIEHS NIH HHS P30 ES001247NIH HHS T32 HL066988NIH HHS U01 AI131344the Strong Children's Research Center Summer Program
6 · The paper itself

Abstract

There has been an increased prevalence of several allergic manifestations such as food allergy, atopic eczema, allergic rhinitis and asthma. Several explanations have been proposed why this has occurred, but one of the main contributing factors may be the gradual loss of microbial exposures over time in regions where allergy is prevalent. Such exposures occur in individuals who practise a traditional farming lifestyle and are protected against allergy. Infant consumption of human milk, more commonly practised in these farming communities, may provide an alternative in combatting allergy, as it known to be beneficial to infant health. In this review, we cover human milk and its role in shaping the gut microbiome promoting the growth of beneficial bacteria like Bifidobacterium, as well as the downstream impact of the farming lifestyle, human milk and Bifidobacterium has on developing infant immunity.

Indexed as

Food HypersensitivityGastrointestinal MicrobiomeAgricultureHumansInfantLife StyleMilk, HumanallergyBifidobacteriumfarminghuman milkinfant immunity

Identifiers

PMID34626494
PMCPMC8678317
OpenAlexW3206277653

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.