Evidence map›Paper›PMID 34626469›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2022

Circulation of Third-Generation Cephalosporin Resistant Salmonella Typhi in Mumbai, India.

Silvia Argimón, Geetha Nagaraj, Varun Shamanna, Dharmavaram Sravani, Ashwini Kodlipet Vasanth, Akshatha Prasanna, Aruna Poojary, Anurag Kumar Bari, Anthony Underwood, Mihir Kekre and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  10. Exploring the bioactive compounds ofFrontiers in cellular and infection microbiology · 2025
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  12. Emergence of carbapenem-resistantFrontiers in microbiology · 2025
    Article
  13. Typhoid fever.Nature reviews. Disease primers · 2023
    Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Silvia ArgimónCentre for Genomic Pathogen Surveillance, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.ORCID 0000-0002-2884-3857
Geetha NagarajCentral Research Laboratory, Kempegowda Institute of Medical Sciences, Bengaluru, India.
Varun ShamannaCentral Research Laboratory, Kempegowda Institute of Medical Sciences, Bengaluru, India.
Dharmavaram SravaniCentral Research Laboratory, Kempegowda Institute of Medical Sciences, Bengaluru, India.
Ashwini Kodlipet VasanthCentral Research Laboratory, Kempegowda Institute of Medical Sciences, Bengaluru, India.
Akshatha PrasannaCentral Research Laboratory, Kempegowda Institute of Medical Sciences, Bengaluru, India.
Aruna PoojaryDepartment of Pathology and Microbiology, Breach Candy Hospital Trust, Mumbai, India.
Anurag Kumar BariDepartment of Pathology and Microbiology, Breach Candy Hospital Trust, Mumbai, India.
Anthony UnderwoodCentre for Genomic Pathogen Surveillance, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.
Mihir KekreCentre for Genomic Pathogen Surveillance, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.
Stephen BakerCambridge Institute of Therapeutic Immunology & Infectious Disease, Department of Medicine, University of Cambridge, Cambridge, United Kingdom.
David M AanensenCentre for Genomic Pathogen Surveillance, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Old Road Campus, Oxford, United Kingdom.
Ravikumar Kadahalli LingegowdaCentral Research Laboratory, Kempegowda Institute of Medical Sciences, Bengaluru, India.
Kempegowda Institute of Medical Sciences · INBreach Candy Hospital · INCentre for Human Genetics · GBUniversity of Cambridge · GB

Funding

Department of Health 16_136_111
6 · The paper itself

Abstract

We report the persistent circulation of third-generation cephalosporin resistant Salmonella Typhi in Mumbai, linked to the acquisition and maintenance of a previously characterized IncX3 plasmid carrying the ESBL gene blaSHV-12 and the fluoroquinolone resistance gene qnrB7 in the genetic context of a triple mutant also associated with fluoroquinolone resistance.

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialSalmonella typhibeta-LactamasesCephalosporinsFluoroquinolonesHumansIndiaMicrobial Sensitivity TestsSalmonellaAnti-Bacterial Agentsbeta-LactamasesCephalosporinsFluoroquinolonesantimicrobial resistance (AMR)extended-spectrum beta lactamases (ESBL)genomic epidemiologythird-generation cephalosporinstyphoid fever

Identifiers

PMID34626469
PMCPMC9258936
OpenAlexW3207851639

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.