Evidence map›Paper›PMID 34626298›Full record

ArticleInternational journal of clinical pharmacy2022

Potentially inappropriate prescribing in a falls clinic using the STOPP and START criteria.

Rosalind Chiam, Nor'izzati Saedon, Hui Min Khor, Sukanya A/P Subramaniam, Siti Sakinah Binti Mohmad Nasir, Noor Fatin Izzati Binti Abu Hashim, Maw Pin Tan

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Article in International journal of clinical pharmacy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rosalind ChiamDepartment of Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.ORCID http://orcid.org/0000-0002-4399-8566
Nor'izzati SaedonDepartment of Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Hui Min KhorDepartment of Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Sukanya A/P SubramaniamFalls and Syncope Service, Cardiorespiratory Laboratory, University of Malaya Medical Centre, 59100, Kuala Lumpur, Malaysia.
Siti Sakinah Binti Mohmad NasirFalls and Syncope Service, Cardiorespiratory Laboratory, University of Malaya Medical Centre, 59100, Kuala Lumpur, Malaysia.
Noor Fatin Izzati Binti Abu HashimFalls and Syncope Service, Cardiorespiratory Laboratory, University of Malaya Medical Centre, 59100, Kuala Lumpur, Malaysia.
Maw Pin TanDepartment of Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. mptan@ummc.edu.my.ORCID http://orcid.org/0000-0002-3400-8540
University Malaya Medical Centre · MYUniversity of Malaya · MY

Funding

Health and Wellbeing Research Cluster, University of Malaya lIRG024A-2019
6 · The paper itself

Abstract

Background Potentially inappropriate prescribing is increasingly common in older patients with falls. However, published indicators to assess inappropriate prescribing remains unestablished in many countries. Objective This study determined the burden and profile of potentially inappropriate prescribing among patients attending a falls clinic using the STOPP/START criteria and evaluated the factors for falls potentially associated to inappropriate prescribing. Setting University of Malaya Medical Centre Falls Clinic. Method Data of individuals aged ≥ 65 years referred to the falls and syncope clinic were extracted from the falls registry. Potentially inappropriate prescribing was determined with the STOPP/START version 2 criteria. The relationship between potentially inappropriate prescribing with polypharmacy (≥ 5 medications), comorbidities and clinical variables were determined using Pearson's chi-square and potential confounders adjusted for with multivariate regression. Main outcome measure Potentially inappropriate medicines and/or omitted medicines using STOPP/START criteria. Results Data from 421 individuals, aged 77.8 ± 6.7 years and 53.4% women, were included. Potentially inappropriate prescribing was present in 311 (73.9%). Potentially inappropriate medicines use accounted for 84.6% of the 325 prescriptions. 361/659 instances (54.8%) were falls-risk-increasing drugs, with vasodilators (49.3%) being the main potentially inappropriate medicine identified. Of the 177/421 with polypharmacy, 169/177 (95.5%) were exposed to ≥ one potentially inappropriate medicine. 129 instances of potentially omitted medicines were observed in 109 prescriptions (25.9%). Conclusion STOPP/START criteria are useful to identify potentially inappropriate prescribing at the falls and syncope clinic. This finding has important implications for medication review strategies at falls clinic. Future research should determine whether identifying potentially inappropriate prescribing may reduce adverse falls outcomes among patients in this setting.

Indexed as

Inappropriate PrescribingPotentially Inappropriate Medication ListAccidental FallsAgedAged, 80 and overAmbulatory Care FacilitiesFemaleHumansMalePolypharmacyAccidental fallsAdverse drug eventsAgedInappropriate prescribingSTOPP START criteria

Identifiers

PMID34626298
OpenAlexW3191902826

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.