Evidence map›Paper›PMID 34626209›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2022

Associations between body composition and vertebral fracture risk in postmenopausal women.

D-P Kuo, Y-W Chiu, P-T Chen, Y-J Tsai, C-H Hou, Y-L Chen, C-M Chu

Abstract read
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In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Role of Body Fat and Metabolic Rate in Site-Specific Fracture Risk: A 20-Year Taiwanese Cohort Study.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

D-P KuoDepartment of Medical Imaging, Taipei Medical University Hospital, No. 252, Wu-Hsing St, Taipei City, 11031, Taiwan.
Y-W ChiuDepartment of Nuclear Medicine, Saint Paul's Hospital, No. 123, Jianxin Street, Taoyuan Dist., Taoyuan County, 33069, Taiwan.
P-T ChenDepartment of Radiology, Kang-Ning General Hospital, No. 26, Lane 420, Section 5, Chenggong Rd., Neihu Dist., Taipei City, 11490, Taiwan.
Y-J TsaiDepartment of Radiology, Keelung Hospital of the Ministry of Health and Welfare, No. 268, Xin 2nd Rd., Xinyi Dist., Keelung City, 20148, Taiwan.
C-H HouDivision of Nuclear Medicine, Taoyuan Armed Forces General Hospital, No. 168, Zhongxing Rd., Longtan Dist., Taoyuan County, 32551, Taiwan.
Y-L ChenDepartment of Radiology, Taoyuan Armed Forces General Hospital, No. 168, Zhongxing Rd., Longtan Dist., Taoyuan County, 32551, Taiwan.
C-M ChuGraduate Institute of Life Sciences, National Defense Medical Center, No. 161, Sec. 6, Minquan E. Rd., Neihu Dist., Taipei City, 11490, Taiwan. chuchiming@web.de.
National Defense Medical Center · TWTaoyuan Armed Forces General Hospital · TWMinistry of Health and Welfare · TWUniversity of Kang Ning · TW

Funding

Taoyuan Armed Forces General Hospital AFTYGH-10630
6 · The paper itself

Abstract

introductionOsteoporosis is a metabolic bone disease with low bone mineral density (BMD) and high incidence of vertebral fractures (VFs). Postmenopausal women with osteoporosis have decreased total fat and lean mass. This study aimed to investigate the associations between body composition and VF risk and explore the potential predictor of VF risk in postmenopausal women.

methodsEnrolled 731 postmenopausal women were referred by various departments and outpatient clinics to assess vertebral status between October 2016 and November 2017. The main measures were total body lean mass, fat mass, and BMD. Patients were divided into osteopenia, osteoporosis, and normal groups based on T-scores. Logistic regression analyses were performed to evaluate associations between body composition parameters and VF.

resultsVF was significantly associated with increased age, lower height, and lighter weight in all participants, and higher BMI was observed in VF participants. Participants in the osteoporosis group were older and had lower height, weight, and BMD than those in normal and osteopenia groups. Femoral and total hip T-scores as well as T-scores for lumbar spine were significantly lower in participants with VF than in non-VF participants. Percentage of bone mass was also significantly lower in VF participants compared to that of non-VF participants. Women with increased BMD and lower bone mass had reduced odds for VF occurrence. Bone mass was significantly able to identify VF occurrence.

conclusionsBody composition analysis discerns differences in the bone status of postmenopausal women with and without VF. The cutoff value of the bone mass might be used effectively as an indicator of risk for VF occurrence.

Indexed as

Osteoporosis, PostmenopausalSpinal FracturesBody CompositionBone DensityFemaleHumansLumbar VertebraePostmenopauseRisk FactorsBody compositionBody mineral density (BMD)OsteopeniaOsteoporosisVertebral fracture

Identifiers

PMID34626209
OpenAlexW3204718954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.