Evidence map›Paper›PMID 34626197›Full record

ArticlePediatric radiology2022

The impact of social distancing during the COVID-19 pandemic on rates of pediatric idiopathic intussusception.

Atsuhiko Handa, Michael J Callahan, Kosuke Kawai, Andy Tsai

Open access · bronzeAbstract read
In one paragraph

Article in Pediatric radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Atsuhiko HandaDepartment of Radiology, Boston Children's Hospital, 300 Longwood Ave., Boston, MA, 02115, USA. atsuhiko.handa@childrens.harvard.edu.ORCID 0000-0001-6401-4629
Michael J CallahanDepartment of Radiology, Boston Children's Hospital, 300 Longwood Ave., Boston, MA, 02115, USA.
Kosuke KawaiInstitutional Centers for Clinical and Translational Research, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
Andy TsaiDepartment of Radiology, Boston Children's Hospital, 300 Longwood Ave., Boston, MA, 02115, USA.
Boston Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe causes of idiopathic ileocolic intussusception are unknown, with infection as the most likely culprit. Recently, social distancing measures were implemented during the coronavirus disease 2019 (COVID-19) pandemic to decrease transmissible infectious diseases, creating an opportune setting to study the role of infection on the pathogenesis of intussusception on a population level.

objectiveTo investigate the impact of social distancing on intussusception. MATERIALS AND

methodsWe retrospectively reviewed air contrast enemas and pylorus ultrasounds performed between March 2010 and March 2021 to identify cases of ileocolic intussusception and hypertrophic pyloric stenosis (HPS), using the latter as a negative control. The study time frame was divided into two periods: pre-pandemic (March 2010-February 2020) and pandemic (April 2020-March 2021). The number of cases that occurred in these two time periods were compared using the Poisson regression model.

resultsOf the 407 cases of idiopathic ileocolic intussusception identified, 396 occurred in the pre-pandemic time period (mean = 39.6 per 12-month period) and 11 occurred in the 12-month pandemic time period. The mean monthly number of intussusceptions showed a decline of 72% (95% confidence interval [CI] 49-85%) between the pre-pandemic and pandemic time periods (3.3 vs. 0.9 monthly cases; P < 0.001). In contrast, the mean monthly number of HPS did not differ significantly (P = 0.19).

conclusionSocial distancing-imposed to curb the spread of infection during the COVID-19 pandemic-resulted in a significant decline in ileocolic intussusception, lending strong support to the theory that infection is the dominant cause of intussusception.

Indexed as

COVID-19IntussusceptionChildHumansPandemicsPhysical DistancingRetrospective StudiesSARS-CoV-2ChildrenCOVID-19Hypertrophic pyloric stenosisIntussusceptionPathogenesisUltrasound

Identifiers

PMID34626197
PMCPMC8501347
OpenAlexW3203325384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.