ArticleThe American journal of clinical nutrition2022
Prepregnancy adherence to plant-based diet indices and exploratory dietary patterns in relation to fecundability.
Article in The American journal of clinical nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Ultra-processed food consumption and risk of infertility in adults: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Preconception dietary patterns and time-to-conception in the high-income multi-country NiPPeR study.Nutrition journal · 2026Trial
- Nutrition in early life, epigenetics and lifelong health - evidence from cohort and intervention studies.The Proceedings of the Nutrition Society · 2025Review
- Do Popular Diets Impact Fertility?Nutrients · 2024Review
- Exploring preconception signatures of metabolites in mothers with gestational diabetes mellitus using a non-targeted approach.BMC medicine · 2023Article
- The Influence of Metabolic Factors and Diet on Fertility.Nutrients · 2023Review
- Modifiable Risk Factor Score and Fecundability in a Preconception Cohort in Singapore.JAMA network open · 2023Article
- Scoping review of the association of plant-based diet quality with health outcomes.Frontiers in nutrition · 2023Article
- Dietary Supplement Intake and Fecundability in a Singapore Preconception Cohort Study.Nutrients · 2022Article
- Pre-pregnancy check-up of maternal vascular status and associated phenotype is crucial for the health of mother and offspring.The EPMA journal · 2022Article
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Authors and funding
14 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundModest associations have been reported between specific food groups or nutrients and fecundability [measured by time to pregnancy (TTP)]. Examining overall diets provides a more holistic approach towards understanding their associations with fecundability. It is not known whether plant-based diets indices or exploratory dietary patterns are associated with fecundability.
objectivesWe examine the associations between adherence to 1) plant-based diet indices; and 2) exploratory dietary patterns and fecundability among women planning pregnancy.
methodsData were analyzed from the Singapore Preconception Study of Long-Term Maternal and Child Outcomes (S-PRESTO) study. Prepregnancy diet was assessed using a semi-quantitative FFQ from which the overall, healthful, and unhealthful plant-based diet indices (oPDI, hPDI, and uPDI, respectively) were calculated. Exploratory dietary patterns were derived using factor analysis based on 44 predefined food groups. Participants were categorized into quintiles based on their dietary pattern scores. TTP (expressed in menstrual cycles) was ascertained within a year from the prepregnancy dietary assessment. Discrete-time proportional hazard models, adjusted for confounders, were used to estimate fecundability ratios (FRs) and 95% CIs, with FR > 1 indicating a shorter TTP.
resultsAmong 805 women, 383 pregnancies were confirmed by ultrasound scans. Compared with women in the lowest quintile, those in the highest quintile of the uPDI had reduced fecundability (FR of Q5 compared with Q1, 0.65; 95% CI, 0.46-0.91; P trend, 0.009). Conversely, greater adherence to the hPDI was associated with increased fecundability (1.46; 95% CI, 1.02-2.07; P trend, 0.036). The oPDI was not associated with fecundability. Among the 3 exploratory dietary patterns, only greater adherence to the Fast Food and Sweetened Beverages (FFSB) pattern was associated with reduced fecundability (0.61; 95% CI, 0.40-0.91; P trend, 0.018).
conclusionsGreater adherence to the uPDI or the FFSB dietary pattern was associated with reduced fecundability among Asian women. Greater adherence to the hPDI may be beneficial for fecundability, though this requires confirmation by future studies.
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