SynthesisInternational journal of biometeorology2022
Crenobalneotherapy for low back pain: systematic review of clinical trials.
Synthesis in International journal of biometeorology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05342051 (The Effects of Immersion in 42℃ Radon, Natrium, Calcium, Bicarbonate Content Thermal-mineral Water on Chronic Low-back Pain. Controlled, Follow-up Study), which is not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects of Immersion in 42℃ Radon, Natrium, Calcium, Bicarbonate Content Thermal-mineral Water on Chronic Low-back Pain. Controlled, Follow-up Study
Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Evidence-based balneotherapy in Hungary. Updated systematic review and meta-analysis of the Hungarian clinical trials.International journal of biometeorology · 2026Pooled it
- Efficacy and safety of balneotherapy in rheumatology: a systematic review and meta-analysis.BMJ open · 2025Pooled it
- Clinical efficacy of peloidotherapy on pain, sleep quality, and central sensitization-related symptoms in chronic low back pain: a comparative analysis.International journal of biometeorology · 2026Trial
- Effects of complex spa therapy in patients with osteoarthritis of the spine receiving treatments in health resorts in south-eastern Poland.Scientific reports · 2022Trial
- Relevance of balneotherapy for back pain-a systematic literature review covering the past 5 years.Wiener medizinische Wochenschrift (1946) · 2025Review
- Hydrogen Sulfide in Balneology: Physiology, Evidence, and Clinical Translation.International journal of molecular sciences · 2025Review
- Effects of bathing in different hot spring types on Japanese gut microbiota.Scientific reports · 2024Article
- Balneotherapy year in review 2021: focus on the mechanisms of action of balneotherapy in rheumatic diseases.Environmental science and pollution research international · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Crenobalneotherapy is a treatment commonly used in Europe and Middle East. It uses mineral water sometimes combined with different hydrotherapy techniques. Most patients treated in spa centers suffer from low back pain. The purpose of this work is to identify clinical trials on crenobalneotherapy for low back pain. Publication research was performed on Medline, Cochrane, and PEDRO databases. Clinical trials were analyzed for internal validity, external validity, quality of statistical analysis, and quality of collection of adverse events. We present the best level of evidence. Bibliographic research identified 21 clinical trials and the coauthors added 5 references. The 26 trials represent 2695 patients. Some have good methodological quality and allow considering crenobalneotherapy as a potential treatment for low back pain, even if the role of mineral water remains uncertain. The methodological quality of therapeutic trials should be improved. These trials should be analyzed in the future guidelines on low back pain.
Indexed as
Identifiers
34625843What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.