ArticleNeuroradiology2022
"Within a minute" detection of focal cortical dysplasia.
Article in Neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Comparison of volume- and surface-based magnetic resonance imaging morphometry algorithms in the detection of focal cortical dysplasia.Epilepsia · 2026Article
- Sleep magnetoencephalography enhances detection and source imaging of seizures and fast oscillations in focal cortical dysplasia.Epilepsia · 2026Article
- Multimodal artificial intelligence in epilepsy: antiseizure medication response, epileptogenic zone localization, and surgical outcome prediction.Frontiers in neurology · 2026Review
- Epilepsy Diagnosis When the Routine Ancillary Tests Are Normal.Neurology international · 2025Review
- Pearls & Oy-sters: Increased Visibility of Focal Cortical Dysplasia in Cerebral MRI During the First Year of Life.Neurology · 2025Article
- Combined MRI morphometry and source imaging guide placement of stereo-EEG electrodes in focal epilepsy with subtle or absent lesions.Frontiers in neurology · 2025Article
- Advances in magnetic resonance imaging for the assessment of paediatric focal epilepsy: a narrative review.Translational pediatrics · 2024Review
- Focal cortical dysplasia (type II) detection with multi-modal MRI and a deep-learning framework.Npj imaging · 2024Article
- The new era of artificial intelligence in neuroradiology: current research and promising tools.Arquivos de neuro-psiquiatria · 2024Article
- A deep learning model for brain segmentation across pediatric and adult populations.Scientific reports · 2024Article
- Machine Learning and Artificial Intelligence Applications to Epilepsy: a Review for the Practicing Epileptologist.Current neurology and neuroscience reports · 2023Review
- Diagnostic Accuracy of Epilepsy-dedicated MRI with Post-processing.Clinical neuroradiology · 2023Article
- An open presurgery MRI dataset of people with epilepsy and focal cortical dysplasia type II.Scientific data · 2023Article
- Prognostic analysis in children with focal cortical dysplasia II undergoing epilepsy surgery: Clinical and radiological factors.Frontiers in neurology · 2023Article
- MRI of focal cortical dysplasia.Neuroradiology · 2022Review
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate a MRI postprocessing tool for the enhanced and rapid detection of focal cortical dysplasia (FCD).
methodsMP2RAGE sequences of 40 consecutive, so far MRI-negative patients and of 32 healthy controls were morphometrically analyzed to highlight typical FCD features. The resulting morphometric maps served as input for an artificial neural network generating a FCD probability map. The FCD probability map was inversely normalized, co-registered to the MPRAGE2 sequence, and re-transferred into the PACS system. Co-registered images were scrolled through "within a minute" to determine whether a FCD was present or not.
resultsFifteen FCD, three subcortical band heterotopias (SBH), and one periventricular nodular heterotopia were identified. Of those, four FCD and one SBH were only detected by MRI postprocessing while one FCD and one focal polymicrogryia were missed, respectively. False-positive results occurred in 21 patients and 22 healthy controls. However, true positive cluster volumes were significantly larger than volumes of false-positive clusters (p < 0.001). The area under the curve of the receiver operating curve was 0.851 with a cut-off volume of 0.05 ml best indicating a FCD.
conclusionAutomated MRI postprocessing and presentation of co-registered output maps in the PACS allowed for rapid (i.e., "within a minute") identification of FCDs in our clinical setting. The presence of false-positive findings currently requires a careful comparison of postprocessing results with conventional MR images but may be reduced in the future using a neural network better adapted to MP2RAGE images.
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