ReviewFEMS microbiology ecology2021
Knowledge gaps in the assessment of antimicrobial resistance in surface waters.
Review in FEMS microbiology ecology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Computational Genomics for Resistome Characterization: Current Advancements and Future Challenges Under a One Health Perspective.Antibiotics (Basel, Switzerland) · 2026Review
- Increased temperature selects for antibiotic resistance genes in a model aquatic ecosystem.npj antimicrobials and resistance · 2026Article
- Persistence of environmental and wastewater-associated antibiotic resistance in river water.Environmental monitoring and assessment · 2026Article
- Burkholderia sp. ZF6-mediated mitigation of Cd and Zn stress in contaminated soil: effects on Chinese cabbage growth and rhizosphere microbial communities.Environmental science and pollution research international · 2026Article
- Green Solutions to a Growing Problem: Harnessing Plants for Antibiotic Removal from the Environment.Antibiotics (Basel, Switzerland) · 2025Review
- Impact of fluoroquinolone and heavy metal pollution on antibiotic resistance maintenance in aquatic ecosystems.Environmental microbiome · 2025Article
- Impact of heavy metals on antibiotic resistance of Escherichia coli from slum wastewater in Kawempe division, Kampala district, Uganda: a case study.BMC microbiology · 2025Article
- Factors influencing the spatial distributions of river microbial communities at the watershed scale: a case study involving the Wuding River Basin.Frontiers in microbiology · 2025Article
- Synergizing Ecotoxicology and Microbiome Data Is Key for Developing Global Indicators of Environmental Antimicrobial Resistance.Microbial ecology · 2024Review
- Bacterial dynamics of the plastisphere microbiome exposed to sub-lethal antibiotic pollution.Microbiome · 2024Article
- A one health approach for monitoring antimicrobial resistance: developing a national freshwater pilot effort.Frontiers in water · 2024Article
- Antimicrobial Resistance Is Prevalent inMicroorganisms · 2023Article
- Review
- Variations in Bacterial Communities and Antibiotic Resistance Genes Across Diverse Recycled and Surface Water Irrigation Sources in the Mid-Atlantic and Southwest United States: A CONSERVE Two-Year Field Study.Environmental science & technology · 2022Article
- Microbial Journey: Mount Everest to Mars.Indian journal of microbiology · 2022Review
- Review of Antimicrobial Resistance in Wastewater in Japan: Current Challenges and Future Perspectives.Antibiotics (Basel, Switzerland) · 2022Review
- Improving the risk assessment of antimicrobial resistance (AMR) along the food/feed chain and from environmental reservoirs using qMRA and probabilistic modelling.EFSA journal. European Food Safety Authority · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The spread of antibiotic resistance in the water environment has been widely described. However, still many knowledge gaps exist regarding the selection pressure from antibiotics, heavy metals and other substances present in surface waters as a result of anthropogenic activities, as well as the extent and impact of this phenomenon on aquatic organisms and humans. In particular, the relationship between environmental concentrations of antibiotics and the acquisition of ARGs by antibiotic-sensitive bacteria as well as the impact of heavy metals and other selective agents on antimicrobial resistance (AMR) need to be defined. Currently, established safety values are based on the effects of antibiotic toxicity neglecting the question of AMR spread. In turn, risk assessment of antibiotics in waterbodies remains a complex question implicating multiple variables and unknowns reinforced by the lack of harmonized protocols and official guidelines. In the present review, we discussed current state-of-the-art and the knowledge gaps related to pressure exerted by antibiotics and heavy metals on aquatic environments and their relationship to the spread of AMR. Along with this latter, we reflected on (i) the risk assessment in surface waters, (ii) selective pressures contributing to its transfer and propagation and (iii) the advantages of metagenomics in investigating AMR. Furthermore, the role of microplastics in co-selection for metal and antibiotic resistance, together with the need for more studies in freshwater are highlighted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.