ArticleEuropean heart journal. Quality of care & clinical outcomes2022
Importance of diagnostic setting in determining mortality in patients with new-onset heart failure: temporal trends in Denmark from 1997 to 2017.
Article in European heart journal. Quality of care & clinical outcomes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Long-term clinical outcomes and healthcare resource utilization in male and female patients following hospitalization for heart failure.European journal of heart failure · 2025Trial
- Prediction of incident heart failure in established atherosclerotic cardiovascular disease: the SMART2-HF model.European heart journal · 2026Article
- Care and Outcomes of New-Onset Heart Failure Across Vulnerable Populations: Temporal Trends in Mortality and Treatment in a Danish Nationwide Cohort From 2003 to 2022.Journal of the American Heart Association · 2026Article
- Outcomes Associated With Early Initiation and Rapid Uptitration of Heart Failure Treatment in Patients With Ejection Fraction <50%: Real-Life Data From the Swedish Heart Failure Registry 2003 to 2022.Journal of the American Heart Association · 2026Article
- Classification of Inpatient and Outpatient Contacts in the Danish National Patient Register: Epidemiological Implications and Future Directions.Clinical epidemiology · 2026Article
- Racial and ethnic disparities in longitudinal trajectories of hospitalizations in patients diagnosed with heart failure.American heart journal · 2025Article
- Long-Term Wildfire Smoke Exposure and Increased Risk of Heart Failure in Older Adults.Journal of the American College of Cardiology · 2025Article
- Inpatient versus outpatient diagnosis of heart failure across the spectrum of ejection fraction: a population cohort study.Heart (British Cardiac Society) · 2025Article
- Awareness, access, and adoption of natriuretic peptides for diagnosis of heart failure.ESC heart failure · 2025Article
- Adherence to guidelines for natriuretic peptide testing in heart failure: a nationwide survey of healthcare professionals in Vietnam.BMJ open · 2025Article
- Association Between Socioeconomic Disadvantage and Risks of Early and Recurrent Admissions Among Patients With Newly Diagnosed Heart Failure.Circulation. Cardiovascular quality and outcomes · 2024Article
- Excess long-term risk of adverse outcomes in heart failure patients with high and low levels of NT-proBNP: A 7-year follow-up study (NorthStar Trial).International journal of cardiology. Heart & vasculature · 2024Article
- Heart failure outcomes by left ventricular ejection fraction in a contemporary region-wide patient cohort.ESC heart failure · 2024Article
- Temporal Trends in the Initiation of Dialysis Among Patients With Heart Failure With or Without Diabetes: A Nationwide Study From 2002 to 2016.Journal of the American Heart Association · 2024Article
- Cardiovascular disease care and outcomes in West and South European countries.The Lancet regional health. Europe · 2023Review
- Recent successes in heart failure treatment.Nature medicine · 2023Review
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate temporal trends in inpatient vs. outpatient diagnosis of new-onset heart failure (HF) and the subsequent risk of death and hospitalization. METHODS AND
resultsUsing nationwide registers, 192 581 patients with a first diagnosis of HF (1997-2017) were included. We computed incidences of HF, age-standardized mortality rates, and absolute risks (ARs) of death and hospitalization (accounting for competing risk of death) to understand the importance of the diagnosis setting in relation to subsequent mortality and hospitalization. The overall incidence of HF was approximately the same (170/100 000 persons) every year during 1997-2017. However, in 1997, 77% of all first diagnoses of HF were made during a hospitalization, whereas the proportion was 39% in 2017. As inpatient diagnoses decreased, outpatient diagnoses increased from 23% to 61%. Outpatients had lower mortality and hospitalization rates than inpatients throughout the study period, although the 1-year age-standardized mortality rate decreased for each inpatient (24 to 14/100-person) and outpatient (11 to 7/100-person). One-year and five-year AR of death decreased by 11.1% and 17.0%, respectively, for all HF patients, while the risk of hospitalization for HF did not decrease significantly (1.13% and 0.96%, respectively).
conclusionBetween 1997 and 2017, HF changed from being primarily diagnosed during hospitalization to being mostly diagnosed in the outpatient setting. Outpatients had much lower mortality rates than inpatients throughout the study period. Despite a significant decrease in mortality risk for all HF patients, neither inpatients nor outpatients experienced a reduction in the risk of an HF hospitalization.
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