ArticleScientific reports2021
Label-free functional and structural imaging of liver microvascular complex in mice by Jones matrix optical coherence tomography.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 26 citations in OpenAlex.
- Differentiating malignancy from liver parenchyma in Ex-Vivo OCT images using anomaly detection.Scientific reports · 2026Article
- High-resolution dynamic full-field optical coherence microscopy: illuminating intracellular activity in deep tissue.Npj imaging · 2026Article
- Dynamic optical coherence tomography algorithm for label-free assessment of swiftness and occupancy of intratissue moving scatterers.Biomedical optics express · 2026Article
- Developmental Imaging of Radish Sprouts Using Dynamic Optical Coherence Tomography.Journal of biophotonics · 2025Article
- Experimental and numerical investigation of wavelength and resolution dependency of dynamic optical coherence tomography signals.Biomedical optics express · 2025Article
- Dynamic-OCT simulation framework based on mathematical models of intratissue dynamics, image formation, and measurement noise.Biomedical optics express · 2025Article
- Optical Coherence Tomography Angiography, Elastography, and Attenuation Imaging for Evaluation of Liver Regeneration.Diagnostics (Basel, Switzerland) · 2025Article
- Neural-network based high-speed volumetric dynamic optical coherence tomography.Biomedical optics express · 2024Article
- Liver microvascular flow evaluation by texture analysis and quantitative contrast-enhanced ultrasound in pediatric chronic liver disease.IEEE South Asian Ultrasonics Symposium · 2024Article
- Renal tubular function and morphology revealed in kidney without labeling using three-dimensional dynamic optical coherence tomography.Scientific reports · 2023Article
- Optical coherence tomography combined with convolutional neural networks can differentiate between intrahepatic cholangiocarcinoma and liver parenchyma ex vivo.Journal of cancer research and clinical oncology · 2023Article
- Optical coherence tomography and convolutional neural networks can differentiate colorectal liver metastases from liver parenchyma ex vivo.Journal of cancer research and clinical oncology · 2023Article
- Dynamic optical coherence tomography for cell analysis [Invited].Biomedical optics express · 2023Review
- Label-free intratissue activity imaging of alveolar organoids with dynamic optical coherence tomography.Biomedical optics express · 2023Article
- Optical coherence microscopy with a split-spectrum image reconstruction method for temporal-dynamics contrast-based imaging of intracellular motility.Biomedical optics express · 2023Article
- Label-free metabolic imaging of non-alcoholic-fatty-liver-disease (NAFLD) liver by volumetric dynamic optical coherence tomography.Biomedical optics express · 2022Article
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11 authors at 2 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
We demonstrate label-free imaging of the functional and structural properties of microvascular complex in mice liver. The imaging was performed by a custom-built Jones-matrix based polarization sensitive optical coherence tomography (JM-OCT), which is capable of measuring tissue's attenuation coefficient, birefringence, and tiny tissue dynamics. Two longitudinal studies comprising a healthy liver and an early fibrotic liver model were performed. In the healthy liver, we observed distinctive high dynamics beneath the vessel at the initial time point (0 h) and reappearance of high dynamics at 32-h time point. In the early fibrotic liver model, we observed high dynamics signal that reveals a clear network vascular structure by volume rendering. Longitudinal time-course imaging showed that these high dynamics signals faded and decreased over time.
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