Evidence map›Paper›PMID 34625416›Full record

ArticleBMJ open2021

Pulse oximetry and supplemental oxygen use in nationwide Veterans Health Administration hospitals, 2013-2017: a Veterans Affairs Patient Database validation study.

Xiao Qing Wang, Theodore Iwashyna, Hallie Prescott, Valeria Valbuena, Sarah Seelye

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xiao Qing WangDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Theodore IwashynaDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Hallie PrescottDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Valeria ValbuenaDepartment of Surgery, University of Michigan, Ann Arbor, Michigan, USA.
Sarah SeelyeAnn Arbor VA Medical Center, Veterans Affairs Center for Clinical Management Research, Ann Arbor, Michigan, USA sarah.seelye@va.gov.ORCID 0000-0001-5098-7470
University of Michigan · USVA Center for Clinical Management Research · US

Funding

Understanding and Informing Early Hospital Antibiotic Prescribing for Potential InfectionR01HS026725 · AHRQ · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIU, VINCENT, PRESCOTT, HALLIE CHRISTINE · 2019 to 2023
$2.2M
AHRQ HHS R01 HS026725
6 · The paper itself

Abstract

objectiveExtraction and standardisation of pulse oximetry and supplemental oxygen data from electronic health records has the potential to improve risk-adjustment, quality assessment and prognostication. We develop an approach to standardisation and report on its use for benchmarking purposes. MATERIALS AND

methodsUsing electronic health record data from the nationwide Veteran's Affairs healthcare system (2013-2017), we extracted, standardised and validated pulse oximetry and supplemental oxygen data for 2 765 446 hospitalisations in the Veteran's Affairs Patient Database (VAPD) cohort study. We assessed face, concurrent and predictive validities using the following approaches, respectively: (1) evaluating the stability of patients' pulse oximetry values during a 24-hour period, (2) testing for greater amounts of supplemental oxygen use in patients likely to need oxygen therapy and (3) examining the association between supplemental oxygen and subsequent mortality.

resultsWe found that 2 700 922 (98%) hospitalisations had at least one pulse oximetry reading, and 864 605 (31%) hospitalisations received oxygen therapy. Patients monitored by pulse oximetry had a reading on average every 6 hours (median 4; IQR 3-7). Patients on supplemental oxygen were older, white and male compared with patients not receiving oxygen therapy (p<0.001) and were more likely to have diagnoses of heart failure and chronic pulmonary diseases (p<0.001). The amount of supplemental oxygen for patients with at least three consecutive values recorded during a 24-hour period fluctuated by median 2 L/min (IQR: 2-3), and 81% of such triplets showed the same level of oxygen receipt.

conclusionOur approach to standardising pulse oximetry and supplemental oxygen data shows face, concurrent and predictive validities as the following: supplemental oxygen clusters in the range consistent with hospital wall-dispensed oxygen supplies (face validity); there are greater amounts of supplemental oxygen for certain clinical conditions (concurrent validity) and there is an association of supplemental oxygen with in-hospital and postdischarge mortality (predictive validity).

Indexed as

AftercareVeteransCohort StudiesHospitalsHumansMaleOximetryOxygenPatient DischargeVeterans HealthOxygenclinical physiologyepidemiologyhealth informaticsrespiratory medicine (see thoracic medicine)

Identifiers

PMID34625416
PMCPMC8504347
OpenAlexW3202592718

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.