Evidence map›Paper›PMID 34625409›Full record

Trial reportCancer prevention research (Philadelphia, Pa.)2021

Novel Models of Genetic Education and Testing for Pancreatic Cancer Interception: Preliminary Results from the GENERATE Study.

C Sloane Furniss, Matthew B Yurgelun, Chinedu Ukaegbu, Pamela E Constantinou, Catherine C Lafferty, Eliana R Talcove-Berko, Alison N Schwartz, Jill E Stopfer, Meghan Underhill-Blazey, Barbara Kenner and 18 more

Open access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Cancer prevention research (Philadelphia, Pa.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. The Use of Telemedicine in Older Patients with Gastrointestinal Diseases.Current treatment options in gastroenterology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 12 institutions in 1 country.

C Sloane FurnissDana-Farber Cancer Institute, Boston, Massachusetts.
Matthew B YurgelunDana-Farber Cancer Institute, Boston, Massachusetts.ORCID 0000-0002-6184-9273
Chinedu UkaegbuDana-Farber Cancer Institute, Boston, Massachusetts.
Pamela E ConstantinouSheikh Ahmed Center for Pancreatic Cancer Research, University of Texas, MD Anderson Cancer Center, Houston, Texas.
Catherine C LaffertyDana-Farber Cancer Institute, Boston, Massachusetts.
Eliana R Talcove-BerkoDana-Farber Cancer Institute, Boston, Massachusetts.
Alison N SchwartzDana-Farber Cancer Institute, Boston, Massachusetts.
Jill E StopferDana-Farber Cancer Institute, Boston, Massachusetts.
Meghan Underhill-BlazeyDana-Farber Cancer Institute, Boston, Massachusetts.
Barbara KennerKenner Family Research Fund, New York, New York.
Scott H NelsonPancreatic Cancer Action Network Volunteer, Patient Advocate, and Pancreatic Cancer Survivor, St. Anthony, Minnesota.
Sydney OkumuraColor Genomics, Burlingame, California.
Sherman LawColor Genomics, Burlingame, California.
Alicia Y ZhouColor Genomics, Burlingame, California.
Tara B CoffinUniversity of Washington, Seattle, Washington.
Nicolette J RodriguezDana-Farber Cancer Institute, Boston, Massachusetts.
Hajime UnoDana-Farber Cancer Institute, Boston, Massachusetts.ORCID 0000-0003-0622-8471
Allyson J OceanWeill Cornell Medical Center, New York, New York.
Florencia McAllisterSheikh Ahmed Center for Pancreatic Cancer Research, University of Texas, MD Anderson Cancer Center, Houston, Texas.
Andrew M LowyMoores Cancer Center, UC San Diego, San Diego, California.ORCID 0000-0002-7106-0735
Scott M LippmanMoores Cancer Center, UC San Diego, San Diego, California.
Alison P KleinJohns Hopkins University, Sol Goldman Pancreatic Cancer Research Center, Baltimore, Maryland.ORCID 0000-0003-2737-8399
Lisa MadlenskyMoores Cancer Center, UC San Diego, San Diego, California.
Gloria M PetersenMayo Clinic, Rochester, Minnesota.
Judy E GarberDana-Farber Cancer Institute, Boston, Massachusetts.ORCID 0000-0001-9449-3982
Michael G GogginsJohns Hopkins University, Sol Goldman Pancreatic Cancer Research Center, Baltimore, Maryland.
Anirban MaitraSheikh Ahmed Center for Pancreatic Cancer Research, University of Texas, MD Anderson Cancer Center, Houston, Texas.
Sapna SyngalDana-Farber Cancer Institute, Boston, Massachusetts. sapna_syngal@dfci.harvard.edu.ORCID 0000-0001-5487-7471
Dana-Farber Cancer Institute · USBrigham and Women's Hospital · USColor (United States) · USThe University of Texas MD Anderson Cancer Center · USUC San Diego Health System · USHarvard University · USUniversity of Baltimore · USMayo Clinic · USNewYork–Presbyterian Hospital · USPancreatic Cancer Action Network · USUnited Hospital Fund · USUniversity of Washington · US

Funding

Tumor Antigens for Individual Signatures and TherapyP50CA062924 · NCI · JOHNS HOPKINS UNIVERSITY · PI JAFFEE, ELIZABETH M. · 1993 to 2022
$54.6M
Tissue CoreP50CA102701 · NCI · MAYO CLINIC ROCHESTER · PI MUKHOPADHYAY, DEBABRATA · 2004 to 2018
$32.7M
Using markers to improve pancreatic cancer screening and surveillance: a multi-center studyU01CA210170 · NCI · JOHNS HOPKINS UNIVERSITY · PI Michael G. Goggins · 2016 to 2026
$9.3M
ALIMENTARY TRACT RESEARCH IN HEALTH AND DISEASET32DK007533 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI BLUMBERG, RICHARD S · 1986 to 2020
$5.3M
Using Markers to Improve Pancreatic Cancer ScreeningR01CA176828 · NCI · JOHNS HOPKINS UNIVERSITY · PI GOGGINS, MICHAEL G. · 2013 to 2024
$4.1M
NCI NIH HHS P50 CA062924NCI NIH HHS P50 CA102701NCI NIH HHS R01 CA176828NCI NIH HHS U01 CA210170NIDDK NIH HHS T32 DK007533
6 · The paper itself

Abstract

Up to 10% of patients with pancreatic ductal adenocarcinoma (PDAC) carry underlying germline pathogenic variants in cancer susceptibility genes. The GENetic Education Risk Assessment and TEsting (GENERATE) study aimed to evaluate novel methods of genetic education and testing in relatives of patients with PDAC. Eligible individuals had a family history of PDAC and a relative with a germline pathogenic variant in

Indexed as

Genetic Predisposition to DiseaseGerm-Line MutationAdolescentAdultAgedAged, 80 and overBRCA1 ProteinBRCA2 ProteinCarcinoma, Pancreatic DuctalFemaleGenetic TestingHumansMaleMiddle AgedModels, GeneticPancreatic NeoplasmsBRCA1 ProteinBRCA1 protein, humanBRCA2 ProteinBRCA2 protein, human

Identifiers

PMID34625409
PMCPMC8563400
OpenAlexW3203563132

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.