Evidence map›Paper›PMID 34625238›Full record

ArticleInjury2022

Predictors of thoracic and lumbar spine injuries in patients with TBI: A nationwide analysis.

Blake M Hauser, John McNulty, Mark M Zaki, Saksham Gupta, David J Cote, Joshua D Bernstock, Yi Lu, John H Chi, Michael W Groff, Ayaz M Khawaja and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Injury, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Blake M HauserComputational Neurosciences Outcomes Center, Department of Neurosurgery, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA. Electronic address: blake_hauser@hms.harvard.edu.
John McNultyComputational Neurosciences Outcomes Center, Department of Neurosurgery, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
Mark M ZakiComputational Neurosciences Outcomes Center, Department of Neurosurgery, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
Saksham GuptaComputational Neurosciences Outcomes Center, Department of Neurosurgery, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
David J CoteComputational Neurosciences Outcomes Center, Department of Neurosurgery, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Joshua D BernstockComputational Neurosciences Outcomes Center, Department of Neurosurgery, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
Yi LuComputational Neurosciences Outcomes Center, Department of Neurosurgery, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
John H ChiComputational Neurosciences Outcomes Center, Department of Neurosurgery, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
Michael W GroffComputational Neurosciences Outcomes Center, Department of Neurosurgery, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
Ayaz M KhawajaComputational Neurosciences Outcomes Center, Department of Neurosurgery, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
Timothy R SmithComputational Neurosciences Outcomes Center, Department of Neurosurgery, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
Hasan A ZaidiComputational Neurosciences Outcomes Center, Department of Neurosurgery, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
Brigham and Women's Hospital · US

Funding

Medical Scientist Training ProgramT32GM007753 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WALENSKY, LOREN DAVID · 1985 to 2021
$50.0M
Training Program in Cancer EpidemiologyT32CA009001 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI A. Heather Eliassen, Meir Stampfer · 1985 to 2026
$17.3M
Etiology of glioma and glioblastomaF30CA235791 · NCI · HARVARD MEDICAL SCHOOL · PI COTE, DAVID JAMES · 2019 to 2020
$85k
NCI NIH HHS F30 CA235791NCI NIH HHS T32 CA009001NIGMS NIH HHS T32 GM007753
6 · The paper itself

Abstract

objectiveCervical spine injury screening is common practice for traumatic brain injury (TBI) patients. However, risk factors for concomitant thoracolumbar trauma remain unknown. We characterized epidemiology and clinical risk for concomitant thoracolumbar trauma in TBI.

methodsWe conducted a multi-center, retrospective cohort analysis of TBI patients in the National Trauma Data Bank from 2011-2014 using multivariable logistic regression.

resultsOut of 768,718 TBIs, 46,654 (6.1%) and 42,810 (5.6%) patients were diagnosed with thoracic and lumbar spine fractures, respectively. Only 11% of thoracic and 7% of lumbar spine fracture patients had an accompanying spinal cord injury at any level. The most common mechanism of injury was motor vehicle accident (67% of thoracic and 71% and lumbar fractures). Predictors for both thoracic and lumbar fractures included moderate (thoracic: OR 1.26, 95%CI 1.21-1.31; lumbar: OR 1.13, 95%CI 1.08-1.18) and severe Glasgow Coma Scale (GCS) score (OR 1.71, 95%CI 1.67-1.75; OR 1.17, 95%CI 1.13-1.20) compared to mild; epidural hematoma (OR 1.36, 95%CI 1.28-1.44; OR 1.1, 95%CI 1.04-1.19); lower extremity injury (OR 1.38, 95%CI 1.35-1.41; OR 2.50, 95%CI 2.45-2.55); upper extremity injury (OR 2.19, 95%CI 2.14-2.23; OR 1.15, 95%CI 1.13-1.18); smoking (OR 1.09, 95%CI 1.06-1.12; OR 1.12, 95%CI 1.09-1.15); and obesity (OR 1.39, 95%CI 1.34-1.45; OR 1.29, 95%CI 1.24-1.35). Thoracic injuries (OR 4.45; 95% CI 4.35-4.55) predicted lumbar fractures, while abdominal injuries (OR 2.02; 95% CI 1.97-2.07) predicted thoracic fractures.

conclusionsWe identified GCS, smoking, upper and lower extremity injuries, and obesity as common risk factors for thoracic and lumbar spinal fractures in TBI.

Indexed as

Brain Injuries, TraumaticSpinal FracturesSpinal InjuriesGlasgow Coma ScaleHumansRetrospective StudiesRehabilitationSpinal fractureTraumatic brain injury

Identifiers

PMID34625238
PMCPMC8863622
OpenAlexW3203185104

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.