Evidence map›Paper›PMID 34625075›Full record

ArticleBMC complementary medicine and therapies2021

Phytochemical screening, antiobesity, antidiabetic and antimicrobial assessments of Orobanche aegyptiaca from Palestine.

Nidal Jaradat, Mohammad Qadi, Iyad Ali, Fatima Hussein, Linda Issa, Doaa Rashdan, Manal Jamoos, Re'as Najem, Abdulraziq Zarour, Mohammad Arar

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC complementary medicine and therapies, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Phytochemical, antioxidant, and antimicrobial properties ofJournal of food science and technology · 2026
    Article
  2. Investigating of the Phytoconstituents, Anti-BioMed research international · 2025
    Article
  3. A comprehensiveFrontiers in pharmacology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Nidal JaradatDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, P.O. Box. 7, Palestine. nidaljaradat@najah.edu.
Mohammad QadiDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, P.O. Box. 7, Palestine. m.qadi@najah.edu.
Iyad AliDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, P.O. Box. 7, Palestine.
Fatima HusseinDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, P.O. Box. 7, Palestine.
Linda IssaDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, P.O. Box. 7, Palestine.
Doaa RashdanDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, P.O. Box. 7, Palestine.
Manal JamoosDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, P.O. Box. 7, Palestine.
Re'as NajemDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, P.O. Box. 7, Palestine.
Abdulraziq ZarourDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, P.O. Box. 7, Palestine.
Mohammad ArarDepartment of Pharmacy, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, P.O. Box. 7, Palestine.
An-Najah National University · PS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicrobial resistance, diabetes mellitus, and obesity are global health care problems that have posed a serious threat to both human and environmental ecosystems. The goals of the present investigations are to investigate the phytoconstituents, antilipase, anti-α-amylase, and antimicrobial activity of Orobanche aegyptiaca Pers. (OA) from Palestine.

methodsIdentification of the phytoconstituents of OA plant petroleum ether, methylene chloride, chloroform, acetone, and methanol extracts were conducted using pharmacopeia's methods, while porcine pancreatic lipase and α-amylase inhibitory activities were examined using p-nitrophenyl butyrate and 3,5-dinitro salicylic acid methods, respectively. Moreover, the antimicrobial activity was evaluated utilizing broth microdilution assay against eight bacterial and fungal strains.

resultsThe phytochemical screening results showed that the methanol extract of the OA plant is rich in phytochemical components, also this extract has powerful antilipase potential with an IC

conclusionThe OA methanol and chloroform extracts could be excellent candidates as antilipase and anti-α-amylase bioactive materials. In addition, methylene chloride, petroleum ether, and chloroform extracts could be potential natural antimicrobial products.

Indexed as

Orobanchealpha-AmylasesAnimalsAnti-Infective AgentsAnti-Obesity AgentsHumansHypoglycemic AgentsLipaseMicrobial Sensitivity TestsMiddle EastPhytochemicalsSwinealpha-AmylasesAnti-Infective AgentsAnti-Obesity AgentsHypoglycemic AgentsLipasePhytochemicalsAntilipaseAntimicrobialAnti-α-amylaseOrobanche aegyptiacaQualitative phytochemistry

Identifiers

PMID34625075
PMCPMC8501537
OpenAlexW3204535839

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.