ArticleBMC genomics2021
Genome-wide investigation and expression profiling of polyphenol oxidase (PPO) family genes uncover likely functions in organ development and stress responses in Populus trichocarpa.
Article in BMC genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Integrated transcriptomic meta-analysis and comparative artificial intelligence models in maize under biotic stress.Scientific reports · 2023Pooled it
- Draft Genome Assembly and Differential Expression ofPlants (Basel, Switzerland) · 2026Article
- Genome-Wide Identification and Expression Analysis of theInternational journal of molecular sciences · 2026Article
- Birth and death evolution of polyphenol oxidase (PPO) gene family in Oryza species.Botanical studies · 2026Article
- Rethinking polyphenol oxidases in wheat: beyond the "low-PPO is always better" paradigm.Frontiers in genetics · 2026Review
- Investigation and characterization of the GhPPO gene family and its expression in response to fibre cell growth and biotic stress in Gossypium hirsutum L.BMC genomics · 2025Article
- Genome-wide identification and expression analysis of the MBD gene family in Broomcorn millet (Panicum miliaceum) and its response to abiotic stress.BMC genomics · 2025Article
- Identification and Expression Analysis of Polyphenol Oxidase Gene Family Members in Response to Wound Stress in Lettuce (Plants (Basel, Switzerland) · 2025Article
- Genome-Wide Identification ofInternational journal of molecular sciences · 2025Article
- Genome-wide analysis of MYB transcription factors in fourFrontiers in plant science · 2025Article
- Identification and Analysis ofPlants (Basel, Switzerland) · 2024Article
- The PPO family in Nicotiana tabacum is an important regulator to participate in pollination.BMC plant biology · 2024Article
- Genome-Wide Analysis of the Polyphenol Oxidase Gene Family inAntioxidants (Basel, Switzerland) · 2023Article
- Aspartyl tRNA-synthetase (AspRS) gene family enhances drought tolerance in poplar through BABA-PtrIBIs-PtrVOZ signaling module.BMC genomics · 2023Article
- Structural and expression analysis of polyphenol oxidases potentially involved in globe artichoke (C. cardunculus var. scolymus L.) tissue browning.Scientific reports · 2023Article
- Genome-Wide Analysis of the FBA Subfamily of the Poplar F-Box Gene Family and Its Role under Drought Stress.International journal of molecular sciences · 2023Article
- Recent Advances of Polyphenol Oxidases in Plants.Molecules (Basel, Switzerland) · 2023Review
- Article
- Genome-wide analysis of the polyphenol oxidase gene family reveals that MaPPO1 and MaPPO6 are the main contributors to fruit browning inFrontiers in plant science · 2023Article
- Recent genome resequencing paraded COBRA-Frontiers in plant science · 2023Article
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTrees such as Populus are planted extensively for reforestation and afforestation. However, their successful establishment greatly depends upon ambient environmental conditions and their relative resistance to abiotic and biotic stresses. Polyphenol oxidase (PPO) is a ubiquitous metalloproteinase in plants, which plays crucial roles in mediating plant resistance against biotic and abiotic stresses. Although the whole genome sequence of Populus trichocarpa has long been published, little is known about the PPO genes in Populus, especially those related to drought stress, mechanical damage, and insect feeding. Additionally, there is a paucity of information regarding hormonal responses at the whole genome level.
resultsA genome-wide analysis of the poplar PPO family was performed in the present study, and 18 PtrPPO genes were identified. Bioinformatics and qRT-PCR were then used to analyze the gene structure, phylogeny, chromosomal localization, gene replication, cis-elements, and expression patterns of PtrPPOs. Sequence analysis revealed that two-thirds of the PtrPPO genes lacked intronic sequences. Phylogenetic analysis showed that all PPO genes were categorized into 11 groups, and woody plants harbored many PPO genes. Eighteen PtrPPO genes were disproportionally localized on 19 chromosomes, and 3 pairs of segmented replication genes and 4 tandem repeat genomes were detected in poplars. Cis-acting element analysis identified numerous growth and developmental elements, secondary metabolism processes, and stress-related elements in the promoters of different PPO members. Furthermore, PtrPPO genes were expressed preferentially in the tissues and fruits of young plants. In addition, the expression of some PtrPPOs could be significantly induced by polyethylene glycol, abscisic acid, and methyl jasmonate, thereby revealing their potential role in regulating the stress response. Currently, we identified potential upstream TFs of PtrPPOs using bioinformatics.
conclusionsComprehensive analysis is helpful for selecting candidate PPO genes for follow-up studies on biological function, and progress in understanding the molecular genetic basis of stress resistance in forest trees might lead to the development of genetic resources.
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