Evidence map›Paper›PMID 34624831›Full record

ReviewNuclear medicine and biology

Radiolabeling with [

Yu-Peng Zhou, Katarina J Makaravage, Pedro Brugarolas

Open access · greenAbstract readReview
In one paragraph

Review in Nuclear medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Recent advances in [Nuclear medicine and biology · 2026
    Review
  2. Modified Reaction Conditions for the Radiosynthesis ofACS medicinal chemistry letters · 2026
    Article
  3. Article
  4. Article
  5. [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  6. Article
  7. Photo- and Cu-MediatedOrganic letters · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Copper-Mediated Radiocyanation of Unprotected Amino Acids and Peptides.Journal of the American Chemical Society · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Yu-Peng ZhouGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Katarina J MakaravageGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Pedro BrugarolasGordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States. Electronic address: pbrugarolas@mgh.harvard.edu.
Gordon Center for Medical Imaging · USHarvard University · US

Funding

Postgraduate Training Program in Medical Imaging (PTPMI)T32EB013180 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Ciprian Catana, Pedram Heidari · 2011 to 2026
$3.7M
Can [18F]3F4AP Detect Brain Demyelination? Evaluation of Novel PET Tracer in Nonhuman Primates and HumansR01NS114066 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI BRUGAROLAS, PEDRO · 2020 to 2024
$1.8M
New tools for imaging: diagnostics based on therapeuticsR00EB020075 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI BRUGAROLAS, PEDRO · 2017 to 2019
$747k
Development of a PET radioligand for alpha2delta-1 receptors to visualize and quantify neuropathic pain mechanisms neuropathic pain mechanismsR21NS120139 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI BRUGAROLAS, PEDRO · 2020 to 2020
$456k
NIBIB NIH HHS R00 EB020075NIBIB NIH HHS T32 EB013180NINDS NIH HHS R01 NS114066NINDS NIH HHS R21 NS120139
6 · The paper itself

Abstract

Hydrogen cyanide (HCN) is a versatile synthon for generating carbon‑carbon and carbon-heteroatom bonds. Unlike other one-carbon synthons (i.e., CO, CO

Indexed as

Carbon RadioisotopesHydrogen CyanideIsotope LabelingPositron-Emission TomographyAnimalsHumansCarbon-11Carbon RadioisotopesHydrogen Cyanide[(11)C]HCNAmino acidsCarbon-11RadiolabelingRadiopharmaceuticalsSugars

Identifiers

PMID34624831
PMCPMC8978408
OpenAlexW3204121968

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.