ArticlePoultry science2021
Hydroxychloride trace elements improved eggshell quality partly by modulating uterus histological structure and inflammatory cytokines expression in aged laying hens.
Article in Poultry science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Organic or Inorganic Zinc for Laying Hens? A Systematic Review and Meta-analysis of the Effects of Zinc Sources on Laying Performance, Egg Quality, and Zinc Excretion.Biological trace element research · 2024Pooled it
- A Genome-Wide Association Study Exploring the Genetic Architecture of Eggshell Quality in Chinese Wenshang Barred Chickens.Animals : an open access journal from MDPI · 2026Article
- Split Feeding for semi-heavy laying hens from 105 to 120 weeks of age: Performance, egg quality, biochemical parameters, reproductive tract morphometry and bone quality.Poultry science · 2026Article
- Optimizing eggshell quality in extended laying periods: Insights and strategies.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Review
- Baicalin alleviates uterine inflammaging and improves eggshell quality in aged laying hens.Frontiers in immunology · 2026Article
- Transcriptome-based analysis reveals relationship between duck eggshell color and eggshell strength.BMC genomics · 2025Article
- Comparison of Hydroxychloride Versus Oxide and Sulfate Sources of Manganese, Zinc, and Copper in Rearing Diets on Pullet Growth, Tibia Traits, and Egg Production and Eggshell Quality in ISA Brown Hens up to 50 Weeks.Animals : an open access journal from MDPI · 2024Article
- Comparative Effects of Including Inorganic, Organic, and Hydroxy Zinc Sources on Growth Development, Egg Quality, Mineral Excretion, and Bone Health of Laying Quails.Biological trace element research · 2024Article
- Methionine supplementation regulates eggshell quality and uterine transcriptome in late-stage broiler breeders.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- Comparative Impact of Hydroxychloride and Organic Sources of Manganese, Zinc, and Copper in Rearing Diets on Pullet Growth, Tibia Traits, Egg Production, and Eggshell Quality in Lohmann Brown Birds up to 50 Weeks of Age.Veterinary sciences · 2024Article
- Transcriptome and histological analyses on the uterus of freckle egg laying hens.BMC genomics · 2023Article
- Genome-Assisted Probiotic Characterization and Application ofMicroorganisms · 2023Article
- The ionome and proteome landscape of aging in laying hens and relation to egg white quality.Science China. Life sciences · 2023Article
- Uterine inflammation status modulates eggshell mineralization via calcium transport and matrix protein synthesis in laying hens.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2023Article
- Effects ofLife (Basel, Switzerland) · 2023Article
- Bacterial communities during composting cultivation of oyster mushroomFrontiers in microbiology · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objectives of this study were to investigate the effectiveness of dietary zinc, copper, and manganese hydroxychloride (HC) supplementation on performance, minerals deposition, serum parameters, eggshell ultrastructure, uterus histological structure, and inflammatory cytokines in aged hens. A total of 560 Hyline Brown layers at 62 wk of age were randomly allotted into 3 groups (CON, basal diet without extra minerals supplemented; Sulphate and HC, basal diet with sulphate or hydroxychloride zinc, copper, and manganese supplementation at levels of 80, 15, and 80 mg/kg, respectively). The trial lasted for 16 wk consisting of 4 wk depletion period and 12 wk testing period. The results indicated that dietary hydroxychloride trace elements increased egg weight (P < 0.05) when compared with CON group and improved average Haugh unit and albumen height (P < 0.05) when compared with Sulphate group from 70 to 73 wk. Trace element supplementation significantly increased eggshell strength, ceruloplasmin content in serum, and modified crystallographic structure of eggshell (P < 0.05) that included effective layer height, palisade height, mammillary layer width, and mammillary internal area ratio, but the results did not differ regarding the trace mineral sources used. Furthermore, hens fed with hydroxychloride trace element showed the highest mucosal fold height (P < 0.05) and epithelial height (P = 0.053) in eggshell gland, as well as mRNA expression of TNF-α (P < 0.05) and IL-22 (P = 0.094). It is concluded that supplementation of Zn, Cu, and Mn mixture modified eggshell quality partly through enhancing histological structure and immune responses of uterus. Hydroxychloride source of Zn, Cu, and Mn excelled sulphate in its beneficial effects for birds.
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