Evidence map›Paper›PMID 34624601›Full record

ArticleRedox biology2021

Oxidized carbon black nanoparticles induce endothelial damage through C-X-C chemokine receptor 3-mediated pathway.

Nairrita Majumder, Murugesan Velayutham, Dimitrios Bitounis, Vamsi K Kodali, Md Habibul Hasan Mazumder, Jessica Amedro, Valery V Khramtsov, Aaron Erdely, Timothy Nurkiewicz, Philip Demokritou and 2 more

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Air pollution and respiratory infections: the past, present, and future.Toxicological sciences : an official journal of the Society of Toxicology · 2023
    Review
  5. Aerosol physicochemical determinants of carbon black and ozone inhalation co-exposure induced pulmonary toxicity.Toxicological sciences : an official journal of the Society of Toxicology · 2023
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Nairrita MajumderDepartment of Physiology and Pharmacology, West Virginia University, School of Medicine, USA; Center for Inhalation Toxicology (iTOX), West Virginia University, School of Medicine, USA.
Murugesan VelayuthamCenter for Inhalation Toxicology (iTOX), West Virginia University, School of Medicine, USA; Department of Biochemistry, West Virginia University, School of Medicine, USA.
Dimitrios BitounisCenter for Nanotechnology and Nanotoxicology, Department of Environmental Health, T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.
Vamsi K KodaliDepartment of Physiology and Pharmacology, West Virginia University, School of Medicine, USA; Center for Inhalation Toxicology (iTOX), West Virginia University, School of Medicine, USA; National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Md Habibul Hasan MazumderDepartment of Physiology and Pharmacology, West Virginia University, School of Medicine, USA; Center for Inhalation Toxicology (iTOX), West Virginia University, School of Medicine, USA.
Jessica AmedroDepartment of Physiology and Pharmacology, West Virginia University, School of Medicine, USA; Center for Inhalation Toxicology (iTOX), West Virginia University, School of Medicine, USA.
Valery V KhramtsovDepartment of Biochemistry, West Virginia University, School of Medicine, USA.
Aaron ErdelyDepartment of Physiology and Pharmacology, West Virginia University, School of Medicine, USA; Center for Inhalation Toxicology (iTOX), West Virginia University, School of Medicine, USA; National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Timothy NurkiewiczDepartment of Physiology and Pharmacology, West Virginia University, School of Medicine, USA; Center for Inhalation Toxicology (iTOX), West Virginia University, School of Medicine, USA; National Institute for Occupational Safety and Health, Morgantown, WV, USA.
Philip DemokritouCenter for Nanotechnology and Nanotoxicology, Department of Environmental Health, T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.
Eric E KelleyDepartment of Physiology and Pharmacology, West Virginia University, School of Medicine, USA; Center for Inhalation Toxicology (iTOX), West Virginia University, School of Medicine, USA.
Salik HussainDepartment of Physiology and Pharmacology, West Virginia University, School of Medicine, USA; Center for Inhalation Toxicology (iTOX), West Virginia University, School of Medicine, USA. Electronic address: salik.hussain@hsc.wvu.edu.
West Virginia University · USHarvard University · US

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI JUDITH FEINBERG · 2012 to 2026
$81.0M
WV INBRE: The Inhibitor of Growth Family Member 4 (ING4) inhibits L-Type Amino Acid Transporter 1 (LAT1) expression to suppress Breast CancerP20GM103434 · NIGMS · MARSHALL UNIVERSITY · PI Travis Salisbury · 2012 to 2026
$61.1M
West Virginia University Stroke COBREP20GM109098 · NIGMS · WEST VIRGINIA UNIVERSITY · PI HRUSKA, MARTIN · 2014 to 2024
$24.5M
Remote Microvascular Dysfunction After Particulate Matter ExposureR01ES015022 · NIEHS · WEST VIRGINIA UNIVERSITY · PI NURKIEWICZ, TIMOTHY R · 2007 to 2021
$4.9M
West Virginia Flow Cytometry Core FacilityP30GM103488 · NIGMS · WEST VIRGINIA UNIVERSITY · PI GIBSON, LAURA F. · 2012 to 2016
$4.8M
Inflammatory cross-talk between heat events and air pollutionR01ES031253 · NIEHS · WEST VIRGINIA UNIVERSITY · PI HUSSAIN, SALIK · 2020 to 2024
$3.5M
Role of Xanthine Oxidase in Heme-induced Vascular DysfunctionR01HL153532 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KELLEY, ERIC EUGENE, STRAUB, ADAM CARL · 2021 to 2024
$2.1M
Targeting Uric Acid as a Therapeutic for NASHR01DK124510 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KELLEY, ERIC EUGENE, KHOO, NICHOLAS · 2020 to 2023
$1.4M
Psychosocial Stress-Induced Vascular Contributions to Cognitive Impairment and Alzheimer's Disease: The Role of Xanthine OxidaseR56NS117754 · NINDS · WEST VIRGINIA UNIVERSITY · PI CHANTLER, PAUL D · 2020 to 2020
$518k
NHLBI NIH HHS R01 HL153532NIDDK NIH HHS R01 DK124510NIEHS NIH HHS R01 ES015022NIEHS NIH HHS R01 ES031253NIGMS NIH HHS P20 GM103434NIGMS NIH HHS P20 GM109098NIGMS NIH HHS P30 GM103488NIGMS NIH HHS U54 GM104942NINDS NIH HHS R56 NS117754
6 · The paper itself

Abstract

Oxidation of engineered nanomaterials during application in various industrial sectors can alter their toxicity. Oxidized nanomaterials also have widespread industrial and biomedical applications. In this study, we evaluated the cardiopulmonary hazard posed by these nanomaterials using oxidized carbon black (CB) nanoparticles (CB

Indexed as

NanoparticlesSootAnimalsLungMiceMice, Inbred C57BLReceptors, ChemokineReceptors, ChemokineSootElectron paramagnetic spectroscopyEndothelial cellsMacrophageNanoparticle carbon blackOxidized carbon blackOzone

Identifiers

PMID34624601
PMCPMC8502956
OpenAlexW3202315329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.