Evidence map›Paper›PMID 34624480›Full record

ArticleToxicology in vitro : an international journal published in association with BIBRA2022

Polyphenol effects on CuO-nanoparticle-mediated DNA damage, reactive oxygen species generation, and fibroblast cell death.

Carlos Angelé-Martínez, Fathima S Ameer, Yash S Raval, Guohui Huang, Tzuen-Rong J Tzeng, Jeffrey N Anker, Julia L Brumaghim

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology in vitro : an international journal published in association with BIBRA, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Toxicity of metal-based nanoparticles: Challenges in the nano era.Frontiers in bioengineering and biotechnology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Carlos Angelé-MartínezDepartment of Chemistry, Clemson University, Clemson, SC 29634-0973, USA. Electronic address: cangele@g.clemson.edu.
Fathima S AmeerDepartment of Chemistry, Clemson University, Clemson, SC 29634-0973, USA. Electronic address: fathima@g.clemson.edu.
Yash S RavalDepartment of Biological Sciences, Clemson University, Clemson, SC 29634, USA. Electronic address: yraval@g.clemson.edu.
Guohui HuangDepartment of Biological Sciences, Clemson University, Clemson, SC 29634, USA. Electronic address: ghuang@clemson.edu.
Tzuen-Rong J TzengDepartment of Biological Sciences, Clemson University, Clemson, SC 29634, USA. Electronic address: tzuenrt@clemson.edu.
Jeffrey N AnkerDepartment of Chemistry, Clemson University, Clemson, SC 29634-0973, USA. Electronic address: janker@clemson.edu.
Julia L BrumaghimDepartment of Chemistry, Clemson University, Clemson, SC 29634-0973, USA. Electronic address: brumagh@clemson.edu.
Clemson University · US

Funding

Targeted Nano-therapeutics for Neural RegenerationP20GM103444 · NIGMS · CLEMSON UNIVERSITY · PI MARKWALD, ROGER R, VYAVAHARE, NAREN R · 2012 to 2018
$14.9M
Investigating Mechanism of Intracellular Rotational Transport with Optical TR15EB014560 · NIBIB · CLEMSON UNIVERSITY · PI ANKER, JEFFREY N · 2012 to 2012
$216k
NIBIB NIH HHS R15 EB014560NIGMS NIH HHS P20 GM103444
6 · The paper itself

Abstract

The ability of ten polyphenolic antioxidants to prevent CuO nanoparticle (

Indexed as

AnimalsCell DeathCell LineCopperDNA DamageFibroblastsHydrogen PeroxideMetal NanoparticlesMicePolyphenolsReactive Oxygen SpeciesCoppercupric oxideHydrogen PeroxidePolyphenolsReactive Oxygen SpeciesCell death preventionCuO nanoparticlesDNA damagePolyphenolProoxidantReactive oxygen species

Identifiers

PMID34624480
PMCPMC8671380
OpenAlexW3202596298

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.