Evidence map›Paper›PMID 34623911›Full record

ArticleScience advances2021

Tox2 is required for the maintenance of GC T

Shu Horiuchi, Hanchih Wu, Wen-Chun Liu, Nathalie Schmitt, Jonathan Provot, Yang Liu, Salah-Eddine Bentebibel, Randy A Albrecht, Michael Schotsaert, Christian V Forst and 2 more

Abstract read
In one paragraph

Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Multimodal features and prognostic risk assessment in locally advanced gastric cancer patients following neoadjuvant therapy based on machine learning algorithms: a multicenter study.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Multimodal analysis definesbioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shu HoriuchiDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0001-5982-0247
Hanchih WuDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-2769-6653
Wen-Chun LiuDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-0344-4371
Nathalie SchmittBaylor Institute for Immunology Research, Baylor Research Institute, Dallas, TX 75204, USA.
Jonathan ProvotBaylor Institute for Immunology Research, Baylor Research Institute, Dallas, TX 75204, USA.
Yang LiuBaylor Institute for Immunology Research, Baylor Research Institute, Dallas, TX 75204, USA.ORCID 0000-0001-7173-6734
Salah-Eddine BentebibelBaylor Institute for Immunology Research, Baylor Research Institute, Dallas, TX 75204, USA.
Randy A AlbrechtDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-4008-503X
Michael SchotsaertDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-3156-3132
Christian V ForstDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0003-0229-9459
Bin ZhangGenetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0002-9549-5653
Hideki UenoDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.ORCID 0000-0001-7747-0738

Funding

Targeting Dendritic Cells for Enhanced Musocal ImmunityU19AI057234 · NIAID · BAYLOR RESEARCH INSTITUTE · PI SEKALY, RAFICK PIERRE · 2003 to 2013
$49.2M
Vaccine Induced Activation of T Follicular Helper Cell SubsetsU19AI089987 · NIAID · BAYLOR RESEARCH INSTITUTE · PI PASCUAL, MARIA VIRGINIA · 2010 to 2015
$17.0M
Scientific CoreU19AI082715 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI PASCUAL, MARIA VIRGINIA · 2009 to 2018
$6.4M
Developing immune reagents to increase the preclinical value of the ferret modelR03AI142046 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ALBRECHT, RANDY A. · 2019 to 2020
$170k
NIAID NIH HHS HHSN272201400008CNIAID NIH HHS R03 AI142046NIAID NIH HHS U19 AI057234NIAID NIH HHS U19 AI082715NIAID NIH HHS U19 AI089987
6 · The paper itself

Abstract

Memory T follicular helper (T

Identifiers

PMID34623911
PMCPMC8500513

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.