Evidence map›Paper›PMID 34623891›Full record

ArticleAIDS patient care and STDs2021

Disparities in Treatment with Direct-Acting Hepatitis C Virus Antivirals Persist Among Adults Coinfected with HIV and Hepatitis C Virus in US Clinics, 2010-2018.

Gina M Simoncini, Qingjiang Hou, Kimberly Carlson, Kate Buchacz, Ellen Tedaldi, Frank Palella, Marcus Durham, Jun Li, HIV Outpatient Study (HOPS) Investigators

Open access · greenAbstract read
In one paragraph

Article in AIDS patient care and STDs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Health Insurance and Initiation of Direct-Acting Antivirals for Hepatitis C in US Women With Human Immunodeficiency Virus.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Gina M SimonciniDepartment of Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-8212-7563
Qingjiang HouCerner Corporation, Kansas City, Missouri, USA.
Kimberly CarlsonCerner Corporation, Kansas City, Missouri, USA.ORCID 0000-0003-2022-8750
Kate BuchaczDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Ellen TedaldiDepartment of Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.
Frank PalellaDepartment of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Marcus DurhamDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Jun LiDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
HIV Outpatient Study (HOPS) Investigators
Centers for Disease Control and Prevention · USCerner (United States) · USTemple University · USNorthwestern University · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

Human immunodeficiency virus (HIV) and hepatitis C virus (HCV) coinfection carries substantial risk for all-cause mortality and liver-related morbidity and mortality, yet many persons coinfected with HIV/HCV remain untreated for HCV. We explored demographic, clinical, and sociodemographic factors among participants in routine HIV care associated with prescription of direct-acting antivirals (DAAs). The HIV Outpatient Study (HOPS) is an ongoing longitudinal cohort study of persons with HIV in care at participating clinics since 1993. There are currently eight study sites in six US cities. We analyzed medical records data of HOPS participants diagnosed with HCV since June 2010. Sustained virological response (SVR) was documented with first undetectable HCV viral load (VL). We assessed factors associated with being prescribed DAAs by multi-variable logistic regression and described the cumulative rate of SVR. Among 306 eligible participants, 131 (43%) were prescribed DAA therapy. Factors associated with greater odds of being prescribed DAA were older age, private health insurance, higher CD4 cell count, being a person who injects drugs, and receiving care at publicly funded sites (

Indexed as

CoinfectionHepatitis CHepatitis C, ChronicHIV InfectionsPharmaceutical PreparationsAdultAgedAntiviral AgentsHepacivirusHumansLongitudinal StudiesTreatment OutcomeAntiviral AgentsPharmaceutical PreparationsDAAHCVhepatitis C treatmentHIV

Identifiers

PMID34623891
PMCPMC10951816
OpenAlexW3203232664

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.