Evidence map›Paper›PMID 34623396›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2022

A Neuroscience Primer for Integrating Geroscience With the Neurobiology of Aging.

Caesar M Hernandez, Abigail R Hernandez, Jessica M Hoffman, Peter H King, Lori L McMahon, Thomas W Buford, Christy Carter, Jennifer L Bizon, Sara N Burke

Abstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Spatial memory and hippocampal remapping: Who will age well?Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  3. Review
  4. Neurobiology of Aging: New Insights From Across the Research Spectrum.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  5. Article
  6. Bridging the Gap: A Geroscience Primer for Neuroscientists With Potential Collaborative Applications.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Caesar M HernandezDepartment of Cellular, Development, and Integrative Biology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0001-9690-5119
Abigail R HernandezEvelyn F. McKnight Brain Institute, The University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0002-3855-4047
Jessica M HoffmanDepartment of Medicine, Division of Gerontology, Geriatrics, and Palliative Care, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Peter H KingDepartment of Cellular, Development, and Integrative Biology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Lori L McMahonDepartment of Cellular, Development, and Integrative Biology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Thomas W BufordEvelyn F. McKnight Brain Institute, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Christy CarterEvelyn F. McKnight Brain Institute, The University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0001-9657-3193
Jennifer L BizonDepartment of Neuroscience, Center for Cognitive Aging and Memory, and the McKnight Brain Institute, The University of Florida, College of Medicine, Gainesville, Florida, USA.
Sara N BurkeDepartment of Neuroscience, Center for Cognitive Aging and Memory, and the McKnight Brain Institute, The University of Florida, College of Medicine, Gainesville, Florida, USA.

Funding

Interdisciplinary Training in Pathobiology and Rehabilitation Medicine.T32HD071866 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JAMES RIMMER, Anna E. Thalacker-Mercer · 2012 to 2026
$4.8M
Consequences of Noradrenergic Degeneration in the Novel TgF344-AD Rat ModelR01AG066489 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MCMAHON, LORI LYNN · 2020 to 2024
$2.9M
Metabolic Interventions for Enhancing Cognitive Resilience in Aging and Alzheimers DiseaseRF1AG060977 · NIA · UNIVERSITY OF FLORIDA · PI BURKE, SARA N · 2019 to 2019
$1.9M
The metabolomic consequences of small size and long lifeR00AG059920 · NIA · AUGUSTA UNIVERSITY · PI HOFFMAN, JESSICA MARIE · 2022 to 2024
$742k
The metabolomic consequences of small size and long lifeK99AG059920 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HOFFMAN, JESSICA MARIE · 2019 to 2021
$342k
NIA NIH HHS K99 AG059920NIA NIH HHS R00 AG059920NIA NIH HHS R01 AG066489NIA NIH HHS RF1 AG060977NIA NIH HHS RF1AG060977NICHD NIH HHS 2T32HD071866-06NICHD NIH HHS T32 HD071866NIH HHS
6 · The paper itself

Abstract

Neuroscience has a rich history of studies focusing on neurobiology of aging. However, much of the aging studies in neuroscience occur outside of the gerosciences. The goal of this primer is 2-fold: first, to briefly highlight some of the history of aging neurobiology and second, to introduce to geroscientists the broad spectrum of methodological approaches neuroscientists use to study the neurobiology of aging. This primer is accompanied by a corresponding geroscience primer, as well as a perspective on the current challenges and triumphs of the current divide across these 2 fields. This series of manuscripts is intended to foster enhanced collaborations between neuroscientists and geroscientists with the intent of strengthening the field of cognitive aging through inclusion of parameters from both areas of expertise.

Indexed as

Cognitive AgingGeroscienceCognitionElectrophysiologyNeurobiologyOptogeneticsPharmacology

Identifiers

PMID34623396
PMCPMC8751809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.