Evidence map›Paper›PMID 34623179›Full record

ArticleAutism : the international journal of research and practice2022

Early diagnosis of autism in the community is associated with marked improvement in social symptoms within 1-2 years.

Nitzan Gabbay-Dizdar, Michal Ilan, Gal Meiri, Michal Faroy, Analya Michaelovski, Hagit Flusser, Idan Menashe, Judah Koller, Ditza A Zachor, Ilan Dinstein

Open access · hybridAbstract read
In one paragraph

Article in Autism : the international journal of research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 3 pooled it
9.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 3 syntheses or guidelines pooled it, 125 citations in OpenAlex.

  1. Pooled it
  2. Who, when, where, and why: A systematic review of "late diagnosis" in autism.Autism research : official journal of the International Society for Autism Research · 2025
    Pooled it
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  9. Grief, Relief, and Belief: A Social Media Study on Late Identification of Neurodivergence.Autism : the international journal of research and practice · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Nitzan Gabbay-DizdarBen-Gurion University of the Negev, Israel.ORCID 0000-0003-0332-3879
Michal IlanBen-Gurion University of the Negev, Israel.
Gal MeiriBen-Gurion University of the Negev, Israel.ORCID 0000-0003-4100-4588
Michal FaroyBen-Gurion University of the Negev, Israel.
Analya MichaelovskiBen-Gurion University of the Negev, Israel.
Hagit FlusserBen-Gurion University of the Negev, Israel.
Idan MenasheBen-Gurion University of the Negev, Israel.ORCID 0000-0003-1961-1461
Judah KollerThe Hebrew University of Jerusalem, Israel.ORCID 0000-0001-9342-9751
Ditza A ZachorTel Aviv University, Israel.ORCID 0000-0002-1766-2487
Ilan DinsteinBen-Gurion University of the Negev, Israel.
Ben-Gurion University of the Negev · ILHebrew University of Jerusalem · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

lay abstractIt is widely believed that early diagnosis and treatment of autism spectrum disorder is essential for better outcome. This is demonstrated by the American Academy of Pediatrics recommendation to screen all 1.5-2.5-year-old toddlers for autism spectrum disorder. However, multiple longitudinal studies of children diagnosed with autism spectrum disorder at 1.5-6 years of age and treated in community settings have not reported any associations between earlier diagnosis and improved outcome in core autism spectrum disorder symptoms. In this study, we measured changes in core autism spectrum disorder symptoms over a 1-2-year period in 131 children diagnosed with autism spectrum disorder at 1.2-5 years of age, and treated in the community. The results revealed that children who were diagnosed before 2.5 years of age were three times more likely to exhibit considerable improvements in social autism spectrum disorder symptoms in comparison to children diagnosed at later ages. These results highlight the importance of early diagnosis and treatment of autism spectrum disorder even in community settings with heterogeneous services. In addition, these results motivate further prioritization of universal screening for autism spectrum disorder before 2.5 years of age.

Indexed as

Autism Spectrum DisorderAutistic DisorderChildChild, PreschoolEarly DiagnosisHumansInfantLongitudinal StudiesMass Screeningautismautism spectrum disorderearly diagnosisoutcomeseverity

Identifiers

PMID34623179
PMCPMC9340129
OpenAlexW3202228182

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.