Evidence map›Paper›PMID 34623174›Full record

ArticleCirculation research2021

Novel Mechanisms of Exosome-Mediated Phagocytosis of Dead Cells in Injured Heart.

Mallikarjun Patil, Sherin Saheera, Praveen K Dubey, Asher Kahn-Krell, Prem Kumar Govindappa, Sarojini Singh, Sultan Tousif, Qinkun Zhang, Hind Lal, Jianyi Zhang and 2 more

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 62 citations in OpenAlex.

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  10. The Potential of Mesenchymal Stem Cell-Derived Exosomes in Cardiac Repair.International journal of molecular sciences · 2024
    Review
  11. Review
  12. Article
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  14. Article
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  17. Article
  18. Article
  19. Article
  20. Exosomes: Methods for Isolation and Characterization in Biological Samples.Methods in molecular biology (Clifton, N.J.) · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Mallikarjun Patil *Department of Biomedical Engineering, Schools of Medicine and Engineering, University of Alabama at Birmingham.
Sherin Saheera *Department of Biomedical Engineering, Schools of Medicine and Engineering, University of Alabama at Birmingham.ORCID 0000-0002-1336-5872
Praveen K DubeyDepartment of Biomedical Engineering, Schools of Medicine and Engineering, University of Alabama at Birmingham.
Asher Kahn-KrellDepartment of Biomedical Engineering, Schools of Medicine and Engineering, University of Alabama at Birmingham.ORCID 0000-0001-7793-3130
Prem Kumar GovindappaDepartment of Biomedical Engineering, Schools of Medicine and Engineering, University of Alabama at Birmingham.ORCID 0000-0001-8069-234X
Sarojini SinghDepartment of Biomedical Engineering, Schools of Medicine and Engineering, University of Alabama at Birmingham.
Sultan TousifDepartment of Biomedical Engineering, Schools of Medicine and Engineering, University of Alabama at Birmingham.
Qinkun ZhangDepartment of Biomedical Engineering, Schools of Medicine and Engineering, University of Alabama at Birmingham.
Hind LalDepartment of Biomedical Engineering, Schools of Medicine and Engineering, University of Alabama at Birmingham.ORCID 0000-0001-8980-9874
Jianyi ZhangDepartment of Biomedical Engineering, Schools of Medicine and Engineering, University of Alabama at Birmingham.ORCID 0000-0002-3955-6554
Gangjian QinDepartment of Biomedical Engineering, Schools of Medicine and Engineering, University of Alabama at Birmingham.
Prasanna KrishnamurthyDepartment of Biomedical Engineering, Schools of Medicine and Engineering, University of Alabama at Birmingham.ORCID 0000-0002-4842-6364
University of Alabama at Birmingham · US

Funding

Signaling Mechanisms Governing Myocardial Fibrosis in Diseased HeartR01HL133290 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Hind Lal · 2017 to 2026
$3.6M
Project-002R01HL143074 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Hind Lal · 2019 to 2026
$3.4M
Mesenchymal Stem Cell Exosome in Efferocytosis of Apoptotic Cardiomyocytes and Repair after Myocardial IschemiaR01HL138023 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KRISHNAMURTHY, PRASANNA, ZHANG, JIANYI · 2018 to 2021
$2.6M
microRNA mediation of Endothelial Progenitor Cell function in Myocardial IchemiaR01HL116729 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KRISHNAMURTHY, PRASANNA · 2013 to 2017
$1.9M
Development and Functional Assessment of Cardiovascular Tissue Engineering Therapy (CVTE) T32 Training GrantT32EB023872 · NIBIB · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROGERS, JACK M, ZHANG, JIANYI · 2018 to 2022
$753k
NHLBI NIH HHS R01 HL116729NHLBI NIH HHS R01 HL133290NHLBI NIH HHS R01 HL138023NHLBI NIH HHS R01 HL143074NIBIB NIH HHS T32 EB023872
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

ApoptosisPhagocytosisAnimalsAntigens, SurfaceCells, CulturedExosomesIntegrinsMacrophagesMaleMiceMice, Inbred C57BLMilk ProteinsMyocardial IschemiaMyocytes, CardiacRAW 264.7 CellsAntigens, SurfaceIntegrinsMfge8 protein, mouseMilk Proteinsexosomesmesenchymal stem cellsopsonin proteinsphosphatidylserinesRNA, small interfering

Identifiers

PMID34623174
PMCPMC8595793
OpenAlexW3203988586

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.