Evidence map›Paper›PMID 34622778›Full record

ArticleeLife2021

Duox-generated reactive oxygen species activate ATR/Chk1 to induce G2 arrest in

Amrutha Kizhedathu, Piyush Chhajed, Lahari Yeramala, Deblina Sain Basu, Tina Mukherjee, Kutti R Vinothkumar, Arjun Guha

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Amrutha KizhedathuRegulation of Cell Fate, Institute for Stem Cell Science and Regenerative Medicine (inStem), Bangalore, India.
Piyush ChhajedRegulation of Cell Fate, Institute for Stem Cell Science and Regenerative Medicine (inStem), Bangalore, India.ORCID 0000-0002-8705-6773
Lahari YeramalaNational Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India.
Deblina Sain BasuRegulation of Cell Fate, Institute for Stem Cell Science and Regenerative Medicine (inStem), Bangalore, India.
Tina MukherjeeRegulation of Cell Fate, Institute for Stem Cell Science and Regenerative Medicine (inStem), Bangalore, India.ORCID 0000-0003-3776-5536
Kutti R VinothkumarNational Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, India.
Arjun GuhaRegulation of Cell Fate, Institute for Stem Cell Science and Regenerative Medicine (inStem), Bangalore, India.ORCID 0000-0002-3753-1484
Institute for Stem Cell Biology and Regenerative Medicine · INTata Institute of Fundamental Research · INUniversity of Trans-Disciplinary Health Sciences and Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progenitors of the thoracic tracheal system of adult

Indexed as

AnimalsCell Cycle ProteinsCheckpoint Kinase 1Drosophila melanogasterDrosophila ProteinsDual OxidasesG2 Phase Cell Cycle CheckpointsProtein Serine-Threonine KinasesReactive Oxygen SpeciesCell Cycle ProteinsCheckpoint Kinase 1Drosophila ProteinsDual Oxidasesgrp protein, DrosophilaMei-41 protein, DrosophilaProtein Serine-Threonine KinasesReactive Oxygen SpeciesATRcell biologyChk1/grapesdevelopmental biologyD. melanogasterDrosophila tracheoblastsDuoxG2 arrestROS

Identifiers

PMID34622778
PMCPMC8594940
OpenAlexW3137127116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.