Evidence map›Paper›PMID 34622667›Full record

ArticleJournal of the American Heart Association2021

Association of Preoperative Diuretic Use With Early Acute Kidney Injury in Infants With Biventricular Hearts Following Cardiac Surgery.

Steven L Rathgeber, Adrija Chakrabarti, Eva Kapravelou, Nicole Hemphill, Christine Voss, Cherry Mammen, Peter Skippen, Kevin C Harris

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Activation of renal epithelial NaFrontiers in pediatrics · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Steven L RathgeberDivision of Pediatric Cardiology Department of Pediatrics Faculty of Medicine University of British Columbia Vancouver Canada.ORCID 0000-0003-4132-5613
Adrija ChakrabartiDivision of Pediatric Cardiology Department of Pediatrics Faculty of Medicine University of British Columbia Vancouver Canada.
Eva KapravelouDivision of Pediatric Cardiology Department of Pediatrics Faculty of Medicine University of British Columbia Vancouver Canada.
Nicole HemphillDivision of Pediatric Cardiology Department of Pediatrics Faculty of Medicine University of British Columbia Vancouver Canada.
Christine VossDepartment of Pediatrics Faculty of Medicine University of British Columbia Vancouver Canada.
Cherry MammenDivision of Nephrology Department of Pediatrics Faculty of Medicine University of British Columbia Vancouver Canada.
Peter SkippenDivision of Critical Care Medicine Department of Pediatrics Faculty of Medicine University of British Columbia Vancouver Canada.
Kevin C HarrisDivision of Pediatric Cardiology Department of Pediatrics Faculty of Medicine University of British Columbia Vancouver Canada.
University of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Diuretics are used to manage congestive heart failure in infants with congenital heart disease. Adult data indicate that preoperative diuretic use increases the risk of cardiac surgery associated acute kidney injury (CS-AKI). We have sought to understand if preoperative diuretics in infants increases the risk of CS-AKI. Methods and Results This is a single-center retrospective study of infants (1-12 months) who had CS requiring cardiopulmonary bypass between 2013 and 2018. The diagnosis and severity of CS-AKI was defined according to the Kidney Disease Improving Global Outcomes guidelines. Three hundred patients were included (mean 6 months, SD 2.4, range 1.2-12.9 months). A total of 149 (49.7%) patients were diagnosed with CS-AKI (stage 1: 80 [54%], stage 2: 57 [38%], stage 3: 12 [8%]). Logistic regression analysis showed preoperative diuretics were not associated with CS-AKI (odds ratio [OR], 0.79; 95% CI, 0.43-1.44;

Indexed as

Acute Kidney InjuryCardiac Surgical ProceduresTetralogy of FallotCardiopulmonary BypassDiureticsHumansPostoperative ComplicationsRetrospective StudiesRisk FactorsDiureticscongenital cardiac defectdiureticskidney

Identifiers

PMID34622667
PMCPMC8751857
OpenAlexW3203223880

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.