ArticleJournal of the American Heart Association2021
Impact of Diastolic Interventricular Septal Flattening on Clinical Outcome in Patients With Severe Tricuspid Regurgitation.
Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Systolic Septal Curvature Ratio as a Cardiac MRI Marker of Right Ventricular Loading in Pediatric Congenital Heart Disease.Pediatric cardiology · 2026Article
- Ultrafast power Doppler imaging for RV myocardial perfusion assessment: histopathologic correlation andEuropean heart journal. Imaging methods and practice · 2026Article
- Review of D-Shape Left Ventricle Seen on Magnetic Resonance Imaging (MRI) or Computed Tomography (CT), Similar to the Movahed Sign Seen on Cardiac Gated Single-Photon Emission Computed Tomography (SPECT) as an Indicator for Right Ventricular Overload.Journal of clinical medicine · 2025Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Little is known about the impact of diastolic interventricular septal flattening on the clinical outcome in patients with severe tricuspid regurgitation. This study sought to evaluate the association of diastolic interventricular septal flattening with clinical outcome in patients with severe tricuspid regurgitation. Methods and Results We retrospectively studied 407 patients who underwent 2-dimensional transthoracic echocardiography and were diagnosed with severe tricuspid regurgitation between January 2014 and December 2015. Cardiovascular events were defined as cardiovascular death or admission for heart failure. The magnitude of interventricular septal flattening was calculated by the eccentricity index (EI) of the left ventricle, and hemodynamic parameters were obtained from transthoracic echocardiography. During follow-up (median, 200 days; interquartile range, 35-1059), 117 of the patients experienced cardiovascular events. By multivariate analysis including potential covariates, EI at end-diastole and left ventricular ejection fraction were independent predictors of cardiovascular events (hazard ratio, 5.33 [1.63-17.41]; hazard ratio, 0.98 [0.97-0.99], respectively). An EI of 1.2 at end-diastole was the optimal cutoff value for identifying poor hemodynamic status defined as cardiac index ≤2.2 L/min per m
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