Evidence map›Paper›PMID 34622609›Full record

ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2021

[Clinical Study of the Impact of

Wan-di Ma, Ping Fan, Hong-Wei Liu, Qing-Qing Liu, Kai-Feng Hu, Huai Bai, Sui-Yan Li

Open access · greenAbstract read
In one paragraph

Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. ACE I/D gene polymorphisms and polycystic ovary syndrome manifestations.Journal of diabetes and metabolic disorders · 2024
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wan-di MaCollege of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China.
Ping FanLaboratory of Genetic Disease and Perinatal Medicine, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Hong-Wei LiuDepartment of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Qing-Qing LiuLaboratory of Genetic Disease and Perinatal Medicine, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Kai-Feng HuLaboratory of Genetic Disease and Perinatal Medicine, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Huai BaiLaboratory of Genetic Disease and Perinatal Medicine, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Sui-Yan LiCollege of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, China.
Southwest Jiaotong University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the relationship between angiotensin Ⅰ-converting enzyme (ACE) insertion/deletion (I/D) gene polymorphism and the genetic risks for polycystic ovary syndrome (PCOS) and to evaluate the impact of ACE I/D genotypes on clinical, hormonal, metabolic and oxidative stress parameters in patients with PCOS.

methodsThis was a retrospective case-control study involving a total of 1 020 PCOS patients and 825 female controls who visited the outpatient clinic of the Department of Reproductive Endocrinology, West China Second Hospital of Sichuan University between 2006 and 2019. The ages of the subjects ranged between 17 and 44. The ACE I/D genotypes were determined by polymerase chain reaction (PCR) and gel electrophoresis. 667 PCOS patients and 527 controls were selected for an analysis of their genotypes and the hormonal, metabolic and oxidative stress parameters.

resultsThe genotype distributions of the

conclusion

Indexed as

Polycystic Ovary SyndromeCase-Control StudiesFemaleGenetic Predisposition to DiseaseHumansPeptidyl-Dipeptidase APolymorphism, Single NucleotideRetrospective StudiesACE protein, humanPeptidyl-Dipeptidase AAngiotensin Ⅰ-converting enzymeGenetic polymorphismOxidative stressPolycysticovarysyndromeSex hormone-binding globulin

Identifiers

PMID34622609
PMCPMC10408884
OpenAlexW3204528766

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.