Evidence map›Paper›PMID 34622597›Full record

ArticleSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2021

[Application of Deep Learning Reconstruction Algorithm in Low-Dose Thin-Slice Liver CT of Healthy Volunteers].

Ling-Ming Zeng, Xu Xu, Wen Zeng, Wan-Lin Peng, Jin-Ge Zhang, Si-Xian Hu, Ke-Ling Liu, Chun-Chao Xia, Zhen-Lin Li

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Article in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Ling-Ming ZengDepartment of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Xu XuDepartment of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Wen ZengDepartment of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Wan-Lin PengDepartment of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Jin-Ge ZhangDepartment of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Si-Xian HuDepartment of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Ke-Ling LiuDepartment of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Chun-Chao XiaDepartment of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Zhen-Lin LiDepartment of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the clinical feasibility of applying deep learning (DL) reconstruction algorithm in low-dose thin-slice liver CT examination of healthy volunteers by comparing the reconstruction algorithm based on DL, filtered back projection (FBP) reconstruction algorithm and iterative reconstruction (IR) algorithm.

methodsA standard water phantom with a diameter of 180 mm was scanned, using the 160 slice multi-detector CT scanning of United Imaging Healthcare, to compare the noise power spectrums of DL, FBP and IR algorithms. 100 healthy volunteers were prospectively enrolled, with 50 assigned to the normal dose group (ND) and 50 to the low dose group (LD). IR algorithm was used in the ND group to reconstruct images, while DL, FBP and IR algorithms were used in the LD group to reconstruct images. One-way analysis of variance was used to compare the liver CT values, the liver noise, liver signal-to-noise ratio (SNR), contrast noise ratio (CNR) and figure of merit (FOM) of the images of ND-IR, LD-FBP, LD-IR and LD-DL. The Kruskal-Wallis test was used to analyse subjective scores of anatomical structures.

resultsThe DL algorithm had the lowest average peak value of noise power spectrum, and its shape was similar to that of medium-level IR algorithm. Liver CT values of ND-IR, LD-FBP, LD-IR and LD-DL did not show statistically significant difference. The noise of LD-DL was lower than that of LD-FBP, LD-IR and ND-IR (

conclusionThe DL algorithm with noise shape similar to the medium iterative grade IR commonly used in clinical practice showed higher noise reduction ability than IR did. Compared with FBP, the DL algorithm had smoother noise shape, but much better noise reduction ability. The application of DL algorithm in low-dose thin-slice liver CT of healthy volunteers can help achieve the standard image quality of liver CT.

Indexed as

Deep LearningAlgorithmsHealthy VolunteersHumansLiverRadiation DosageRadiographic Image Interpretation, Computer-AssistedTomography, X-Ray ComputedDeep learningImage reconstructionLiver computed tomography

Identifiers

PMID34622597
PMCPMC10408901

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